The objective of our Hazard Identification Core [HIC] (Core C) is to provide state-of-the-art chemical analytical services that will be utilized by all of the Biomedical and Environmental Sciences Research Projects and by the studies that are associated with the Research Translation and Outreach Cores. The Metals Analysis Laboratory of the HIC has been providing total metal and arsenic speciation analyses for our UA SBRP research projects resulting in data for numerous publications. In this renewal we will expand the services of this Core by including the Arizona Laboratory for Emerging Contaminant (ALEC) as another analytical site. ALEC will provide additional metal speciation analyses, particle size and chemistry analyses, and organic pollutant analyses.
The Specific Aims of this Core are: 1. Metals Analysis Laboratory will provide routine total metal analysis. 2. Metal Analysis Laboratory will provide routine arsenic speciation analysis. 3. ALEC will provide analyses for solution phase speciation of selected metal(loid)s other than arsenic. 4. ALEC will provide analysis of size and chemical composition of contaminant-containing particles. 5. ALEC will provide routine and specialty analysis of organic contaminants and degradation products in environmental samples. By supplying and expanding the HIC analytical services, our UA SBRP investigators will have access to constantly improving technological capabilities in order to meet the aims of their basic scientific investigations (biomedical, environmental science, engineering, and remediation). By providing expert staff support, investigators are not burdened by concerns of having to develop and perform advanced analytical procedures that are costly in terms of personnel, laboratory space, and supplies. The HIC has been and will be an exceptional asset for facilitating the research of UA SBRP investigators.

Public Health Relevance

Chemical analysis of environmental pollutants is needed to assess environmental contamination, levels of exposure, and the disposition of contaminants. These analyses that are needed to perform proper risk assessment of environmental pollutants.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
2P42ES004940-21
Application #
7936615
Study Section
Special Emphasis Panel (ZES1-LWJ-M (O1))
Project Start
2010-04-01
Project End
2015-03-31
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
21
Fiscal Year
2010
Total Cost
$130,668
Indirect Cost
Name
University of Arizona
Department
Type
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Pu, Mengjie; Guan, Zeyu; Ma, Yongwen et al. (2018) Synthesis of iron-based metal-organic framework MIL-53 as an efficient catalyst to activate persulfate for the degradation of Orange G in aqueous solution. Appl Catal A Gen 549:82-92
Brusseau, Mark L; Guo, Zhilin (2018) The integrated contaminant elution and tracer test toolkit, ICET3, for improved characterization of mass transfer, attenuation, and mass removal. J Contam Hydrol 208:17-26
Valentín-Vargas, Alexis; Neilson, Julia W; Root, Robert A et al. (2018) Treatment impacts on temporal microbial community dynamics during phytostabilization of acid-generating mine tailings in semiarid regions. Sci Total Environ 618:357-368
Brusseau, Mark L (2018) Assessing the potential contributions of additional retention processes to PFAS retardation in the subsurface. Sci Total Environ 613-614:176-185
Delikhoon, Mahdieh; Fazlzadeh, Mehdi; Sorooshian, Armin et al. (2018) Characteristics and health effects of formaldehyde and acetaldehyde in an urban area in Iran. Environ Pollut 242:938-951
Hammond, Corin M; Root, Robert A; Maier, Raina M et al. (2018) Mechanisms of Arsenic Sequestration by Prosopis juliflora during the Phytostabilization of Metalliferous Mine Tailings. Environ Sci Technol 52:1156-1164
Yan, Ni; Zhong, Hua; Brusseau, Mark L (2018) The natural activation ability of subsurface media to promote in-situ chemical oxidation of 1,4-dioxane. Water Res 149:386-393
Madeira, Camila L; Field, Jim A; Simonich, Michael T et al. (2018) Ecotoxicity of the insensitive munitions compound 3-nitro-1,2,4-triazol-5-one (NTO) and its reduced metabolite 3-amino-1,2,4-triazol-5-one (ATO). J Hazard Mater 343:340-346
Liu, Pengfei; Rojo de la Vega, Montserrat; Sammani, Saad et al. (2018) RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression. Proc Natl Acad Sci U S A 115:E10352-E10361
Thomas, Andrew N; Root, Robert A; Lantz, R Clark et al. (2018) Oxidative weathering decreases bioaccessibility of toxic metal(loid)s in PM10 emissions from sulfide mine tailings. Geohealth 2:118-138

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