The UNC Superfund Basic Research Program (SBRP) involves six research projects, two research cores, and support cores. The research components of the Program rely heavily on graduate students and postdoctoral associates. The Training Core provides the structure needed to ensure that research personnel acquire broad interdisciplinary and multidisciplinary training in the biomedical and non-biomedical sciences, as well as in practical aspects of Superfund. All of the Project and Core Leaders in the UNC SBRP reside in the Department of Environmental Sciences and Engineering in the School of Public Health. Elements of the existing interdisciplinary culture in the Department will be combined with SBRP-specific training elements to provide an efficient, comprehensive, and relevant training experience for our students and post-docs. The components of the Core will include seminar programs, formal course work, short courses, retreats, conferences, internships, and collaborations. Trainees will emerge not only with the deep understanding resulting from focus on an individual research aim, but also with a broad grounding in many aspects of Superfund and with skills in interdisciplinary and multidisciplinary approaches to understanding and protecting public health. A strong commitment to, and record of accomplishment in, the training of underrepresented groups is documented. The Program and Core have benefited in this regard from other established programs on campus intended to benefit underrepresented groups.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES005948-16
Application #
7599095
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
16
Fiscal Year
2008
Total Cost
$75,691
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Adebambo, Oluwadamilare A; Shea, Damian; Fry, Rebecca C (2018) Cadmium disrupts signaling of the hypoxia-inducible (HIF) and transforming growth factor (TGF-?) pathways in placental JEG-3 trophoblast cells via reactive oxygen species. Toxicol Appl Pharmacol 342:108-115
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Balik-Meisner, Michele; Truong, Lisa; Scholl, Elizabeth H et al. (2018) Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure. Environ Health Perspect 126:067010
To, Kimberly T; Fry, Rebecca C; Reif, David M (2018) Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi. BioData Min 11:10
Dalaijamts, Chimeddulam; Cichocki, Joseph A; Luo, Yu-Syuan et al. (2018) Incorporation of the glutathione conjugation pathway in an updated physiologically-based pharmacokinetic model for perchloroethylene in mice. Toxicol Appl Pharmacol 352:142-152

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