(Taken from application) The proposed Community-based Prevention and Intervention (CBPI) project -- Preventing Fetal Neurotoxicity by Reducing Local Fish Consumption: An Educational Intervention among Women Receiving WIC Services in New York City) -- will translate the scientific findings from the Mount Sinai School of Medicine?s Superfund Basic Research Program into a direct preventive action designed to reduce human exposure to toxic chemicals found in New York City waterways. The goal of this project is to prevent fetal neurotoxicity caused by PCBs and other persistent pollutants by reducing consumption of locally caught fish among women of childbearing age in two low-income communities (East Harlem and the South Bronx) where subsistence fishing is common. Previous SBRP research confirms that fish and shellfish taken from waters near these communities contain unsafe levels of PCBs and other toxins, posing special risks for women of childbearing age even at relatively low doses. Surveys of local anglers show that many are unaware of the hazards to health that result from consumption of local fish; even when informed, many still eat their catch; the catch is shared with friends and families, including women of childbearing age; and some of the catch is illegally sold. The anglers hold inaccurate but deeply felt beliefs about the safety of local fish, and they tend to distrust government advisories. Women of childbearing age in the study communities may be more open than men to information about fetal health, and are also the population at highest risk. Accordingly, the proposed project will work with eight local WIC (Special Supplemental Nutritional Support for Women, Infants and Children) centers to develop and test a theory-based, culturally appropriate, participatory behavioral approach for promoting safer choices and practices related to consumption of local fish and shellfish. The project is being developed in close collaboration with the New York State Department of Health, state WIC administrators and the WIC center directors. Community organizations are linked to the project through the Outreach Core. Consultants associated with the project add multidisciplinary expertise in social and behavioral science, community-based program development and evaluation, and research and intervention in low-income minority communities.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
2P42ES007384-06
Application #
6480312
Study Section
Special Emphasis Panel (ZES1)
Project Start
1995-05-01
Project End
2006-03-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Type
DUNS #
114400633
City
New York
State
NY
Country
United States
Zip Code
10029
Yan, Beizhan; Bopp, Richard F; Abrajano, Teofilo A et al. (2014) Source apportionment of polycyclic aromatic hydrocarbons (PAHs) into Central Park Lake, New York City, over a century of deposition. Environ Toxicol Chem 33:985-92
Miller, Todd R; Colquhoun, David R; Halden, Rolf U (2010) Identification of wastewater bacteria involved in the degradation of triclocarban and its non-chlorinated congener. J Hazard Mater 183:766-72
Miller, Todd R; Heidler, Jochen; Chillrud, Steven N et al. (2008) Fate of triclosan and evidence for reductive dechlorination of triclocarban in estuarine sediments. Environ Sci Technol 42:4570-6
Landrigan, Philip J; Forman, Joel; Galvez, Maida et al. (2008) Impact of September 11 World Trade Center disaster on children and pregnant women. Mt Sinai J Med 75:129-34
Louchouarn, Patrick; Chillrud, Steven N; Houel, Stephane et al. (2007) Elemental and molecular evidence of soot- and char-derived black carbon inputs to New York City's atmosphere during the 20th century. Environ Sci Technol 41:82-7
Grandjean, P; Landrigan, P J (2006) Developmental neurotoxicity of industrial chemicals. Lancet 368:2167-78
Wallenstein, Sylvan; Chen, Jia; Wetmur, James G (2006) Comparison of statistical models for analyzing genotype, inferred haplotype, and molecular haplotype data. Mol Genet Metab 89:270-3
Trasande, Leonardo; Schechter, Clyde; Haynes, Karla A et al. (2006) Applying cost analyses to drive policy that protects children: mercury as a case study. Ann N Y Acad Sci 1076:911-23
Ma, Risheng; Sassoon, David A (2006) PCBs exert an estrogenic effect through repression of the Wnt7a signaling pathway in the female reproductive tract. Environ Health Perspect 114:898-904
Gobeille, Alayne K; Morland, Kimberly B; Bopp, Richard F et al. (2006) Body burdens of mercury in lower Hudson River area anglers. Environ Res 101:205-12

Showing the most recent 10 out of 50 publications