For almost 15 years in total, the DUSRC Research Translation Core (RTC) has worked to accelerate the application of Center?s research in order to prevent or reduce early life, developmental exposures through strategic networks, partnerships, and other activities. The RTC will continue our work with Investigators from each Project to identify key stakeholders with the capacity to influence early life exposures or their outcomes. At least three times per year, the RTC will organize practical trainings in research translation and science communication for all Center members. These communication trainings may include RTC-led workshops in monthly Center meetings and sessions led by outside experts. The RTC will collaborate with the Training Core, the CEC, and the Administrative Core to implement a structured program of trainee involvement with research translation and community engagement activities each year of their SRP funding, named the Trainee Communication and Engagement Program (TCEP). The RTC will also work in coordination with the CEC to create and mentor Trainee Response Teams (TRT) to respond to short-term requests by community-based organizations, industry, or policy makers for information related to one of the Center?s areas of expertise. Duke?s new student electronic portfolio (ePortfolio) system, PebblePad?, will be used by each trainee to store, document, publish, and distribute artifacts developed during their TCEP. To most effectively engage SRP?s key stakeholders, ATSDR and EPA, around Center findings, the RTC will expand an existing collaboration with the University of Kentucky and University of North Carolina Superfund Research Centers to form a partnership at renewal with all SRCs in EPA Regions 3 and 4. The DUSRC has a long-standing partnership with the Elizabeth River Project (ERP) in conjunction with Project 3; at renewal, we propose a deeper research translation partnership with ERP and other area stakeholders. To communicate and contextualize the implications of the DUSRC?s findings to health professionals who work with women, infants, and children, as well as to broad audiences, the RTC will strategically employ online communication efforts to disseminate timely environmental health resources to existing stakeholders and other identified partners. In particular, RTC will engage both broad audiences and targeted professional leaders who are focused on developmental exposures through their existing communities. The RTC will work with DUSRC PIs to develop summaries, review articles, and editorial pieces about managing risks from environmental exposures for OB/GYN periodicals or other appropriate resource centers. RTC staff and interns will manage the DUSRC website (sites.nicholas.duke.edu/superfund) and will work with the Admin Core, PIs, and trainees to ensure that each project and core webpage concisely shares our latest findings, research direction, and news/media publicity.

Public Health Relevance

For almost 15 years in total, the DUSRC Research Translation Core (RTC) has worked to clearly and accurately describe the work of our scientists to external stakeholders, such as those in the US EPA, ATSDR, state and local governments, and non-governmental organizations. Collaboration and communication with other Superfund Research Centers is also key to our work. We also work to engage our doctoral students and post-doctoral fellows in developing their own skills in research translation during their time at Duke.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010356-18
Application #
9942430
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
18
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Meyer, Joel N; Hartman, Jessica H; Mello, Danielle F (2018) Mitochondrial Toxicity. Toxicol Sci 162:15-23
Oliveri, Anthony N; Ortiz, Erica; Levin, Edward D (2018) Developmental exposure to an organophosphate flame retardant alters later behavioral responses to dopamine antagonism in zebrafish larvae. Neurotoxicol Teratol 67:25-30
Slotkin, Theodore A; Skavicus, Samantha; Seidler, Frederic J (2018) Developmental neurotoxicity resulting from pharmacotherapy of preterm labor, modeled in vitro: Terbutaline and dexamethasone, separately and together. Toxicology 400-401:57-64
Lefèvre, Emilie; Bossa, Nathan; Gardner, Courtney M et al. (2018) Biochar and activated carbon act as promising amendments for promoting the microbial debromination of tetrabromobisphenol A. Water Res 128:102-110
Kollitz, Erin M; Kassotis, Christopher D; Hoffman, Kate et al. (2018) Chemical Mixtures Isolated from House Dust Disrupt Thyroid Receptor ? Signaling. Environ Sci Technol :
Hartman, Jessica H; Smith, Latasha L; Gordon, Kacy L et al. (2018) Swimming Exercise and Transient Food Deprivation in Caenorhabditis elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity. Sci Rep 8:8359
Luz, Anthony L; Kassotis, Christopher D; Stapleton, Heather M et al. (2018) The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPAR? activation, in 3T3-L1 cells. Toxicology 393:150-159
Day, D B; Xiang, J; Mo, J et al. (2018) Combined use of an electrostatic precipitator and a high-efficiency particulate air filter in building ventilation systems: Effects on cardiorespiratory health indicators in healthy adults. Indoor Air 28:360-372
Slotkin, Theodore A; Ko, Ashley; Seidler, Frederic J (2018) Does growth impairment underlie the adverse effects of dexamethasone on development of noradrenergic systems? Toxicology 408:11-21
Rock, Kylie D; Horman, Brian; Phillips, Allison L et al. (2018) EDC IMPACT: Molecular effects of developmental FM 550 exposure in Wistar rat placenta and fetal forebrain. Endocr Connect 7:305-324

Showing the most recent 10 out of 291 publications