The long-term goal of Project #4 is to better understand the relationship between the observed concentrations in ambient air and specific sources of airborne PCBs in residential and industrial communities. The central hypothesis is that emissions of airborne PCBs are a function of measureable and quantifiable characteristics of the physical-chemical characteristics of the compounds and exposed environmental surfaces on which the PCBs reside.
The Aims focus on identification, characterization and prediction of the magnitude and impact of sources of airborne PCBs:
Aim 1 : To determine the sources and fate of airborne PCB congeners in the urban/industrial complex of Chicago. We hypothesize that airborne PCBs in Chicago originate from contaminated surfaces throughout the city. We will test our hypotheses by deploying air samplers throughout the City of Chicago and over seasons. Using the measurements, models, and geographic databases, we will determine the relative contribution of Chicago sources toward the annual mass of PCBs deposited in Lake Michigan, distinguish long range versus local sources of airborne PCBs to the region, and determine neighborhoods of elevated risk for high exposure to airborne PCBs.
Aim 2 : To chapacterize the sources and Aroclor PCBs. We hypothesize that non-Aroclor PCBs have beeN released to the environment for decades and conthnue to be released due to their presence in commercial paint and other buil$ing materials. We wihl test this hypothesis by measuring non-Aroclor PCBs in archival and new samples and by measuring PCBs in c/mmercial paint. Using sediment cores and archived sample extracts, we will ddtermine the chronology of environmental exposure to these compounds and the magnitude of their current emissions.
Aim 3 : To characterize the emission and fate of airborne PCBs in the Indiana Harbor and Ship Canal (IHSC). We hypothesize that the sediment of the IHSC is a major source of airborne PCB congeners to the community of East Chicago, Indiana. To test our hypotheses, we will measure PCBs in deep sediments of the IHSC. We will calculate the release of PCBs under no-dredging and dredging-conditions, including partial Removal that exposes deep sediments. We will monitor the effect of dredging through local and regional air measurements. As a result of the work described here, Project #4 will promote more scientifically-sound and effective action to reduce human exposure to these potentially harmful compounds.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES013661-09
Application #
8659478
Study Section
Special Emphasis Panel (ZES1-LWJ-M)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
9
Fiscal Year
2014
Total Cost
$260,828
Indirect Cost
$72,021
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Hou, Xingwang; Yu, Miao; Liu, Aifeng et al. (2018) Biotransformation of tetrabromobisphenol A dimethyl ether back to tetrabromobisphenol A in whole pumpkin plants. Environ Pollut 241:331-338
Xiao, Xin; Chen, Baoliang; Chen, Zaiming et al. (2018) Insight into Multiple and Multilevel Structures of Biochars and Their Potential Environmental Applications: A Critical Review. Environ Sci Technol 52:5027-5047
Herkert, Nicholas J; Jahnke, Jacob C; Hornbuckle, Keri C (2018) Emissions of Tetrachlorobiphenyls (PCBs 47, 51, and 68) from Polymer Resin on Kitchen Cabinets as a Non-Aroclor Source to Residential Air. Environ Sci Technol 52:5154-5160
P?n?íková, Kate?ina; Svržková, Lucie; Strapá?ová, Simona et al. (2018) In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion. Environ Pollut 237:473-486
P?n?íková, Kate?ina; Brenerová, Petra; Svržková, Lucie et al. (2018) Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro. Environ Sci Pollut Res Int 25:16411-16419
Robertson, Larry W; Weber, Roland; Nakano, Takeshi et al. (2018) PCBs risk evaluation, environmental protection, and management: 50-year research and counting for elimination by 2028. Environ Sci Pollut Res Int 25:16269-16276
Klaren, William D; Vine, David; Vogt, Stefan et al. (2018) Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25:16427-16433
Tomsho, Kathryn S; Basra, Komal; Rubin, Staci M et al. (2018) Correction to: Community reporting of ambient air polychlorinated biphenyl concentrations near a Superfund site. Environ Sci Pollut Res Int 25:16401
Uwimana, Eric; Li, Xueshu; Lehmler, Hans-Joachim (2018) Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite. Environ Sci Technol 52:6000-6008
Herkert, Nicholas J; Hornbuckle, Keri C (2018) Effects of room airflow on accurate determination of PUF-PAS sampling rates in the indoor environment. Environ Sci Process Impacts 20:757-766

Showing the most recent 10 out of 298 publications