The Puerto Rico Testsite for Exploring Contamination Threats Center (PROTECT) uses an integrated, cross- disciplinary approach to study the fate, transport, exposure, health impact and remediation of contaminants commonly found at Superfund sites, with particular attention to phthalates and chlorinated solvents as both are suspect and model agents in the high preterm birth rates in Puerto Rico. The Research Translation Core (RTC) serves the overall interests of PROTECT and NIEHS by translating and disseminating PROTECT research results to a wide variety of governmental agencies, scientific communities, industry, and other stakeholders. The RTC does this through five aims: ? Aim 1: Publicize and emphasize to EPA, ATSDR, and other stakeholders the significance and/or relevance of program findings for public policy, public health, and prevention ? Aim 2: Build partnerships with stakeholders to respond to requests, develop capacity, and improve understanding of Center findings ? Aim 3: Serve as the bridge between investigators, partners and stakeholders to foster commercial development, utilization and translation of the knowledge gained by the SRP program into tools, strategies or technologies, in an efficient and timely manner ? Aim 4: Collaborate with other PROTECT cores for enhanced sharing of information, materials and best practices outside of PROTECT ? Aim 5: Communicate PROTECT work to SRP Headquarters and to the national SRP community These aims are realized through activities that solidify internal communications within PROTECT, communications with other SRPs and the national office, and communication with a wide range of professional, governmental, public health, and community organizations. The RTC works with each project leader to develop translational activities, and it offers training sessions for faculty, postdocs, and students to facilitate research translation. The RTC develops mechanisms for technology transfer, such as patents, commercialization, and intellectual property. It facilitates consultations of expertise and new collaborations, particularly outside the SRP community. The RTC helps investigators to increase NIEHS and other grant submissions, thus expanding the environmental health capacity of the constituent campuses. It offers webinars and conferences to share findings and for communities to share experiences/needs with the university researchers, especially by collaborating with the Training Core and Community Engagement Core. The RTC has a strong website presence and is the central clearinghouse for collating and disseminating PROTECT results and materials. The RTC also develops publications that highlight the overall sum of PROTECT's research translation outcomes.

Public Health Relevance

PROTECT uses an integrated, cross-disciplinary approach to study the transport, exposure, health impact and remediation of contaminants commonly found at Superfund sites, with particular attention to phthalates and chlorinated solvents as both are suspect in the high preterm birth rates in Puerto Rico. The Research Translation Core coordinates PROTECT's efforts to translate and disseminate research results from all Center projects to stakeholders, to promote understanding of contaminant exposure and assist in public health education and intervention.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
2P42ES017198-05
Application #
8649390
Study Section
Special Emphasis Panel (ZES1-LKB-K (S))
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
5
Fiscal Year
2014
Total Cost
$123,887
Indirect Cost
$44,217
Name
Northeastern University
Department
Type
DUNS #
001423631
City
Boston
State
MA
Country
United States
Zip Code
02115
Elkin, Elana R; Harris, Sean M; Loch-Caruso, Rita (2018) Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line. Toxicol Appl Pharmacol 338:30-42
Aker, Amira M; Johns, Lauren; McElrath, Thomas F et al. (2018) Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study. Environ Int 113:341-349
Xue, Yunfei; Rajic, Ljiljana; Chen, Long et al. (2018) Electrolytic control of hydrogen peroxide release from calcium peroxide in aqueous solution. Electrochem commun 93:81-85
Taqieddin, Amir; Allshouse, Michael R; Alshawabkeh, Akram N (2018) Review-Mathematical Formulations of Electrochemically Gas-Evolving Systems. J Electrochem Soc 165:E694-E711
Yu, Xue; Feric, Zlatan; Cordero, José F et al. (2018) Potential influence of temperature and precipitation on preterm birth rate in Puerto Rico. Sci Rep 8:16106
Koman, Patricia D; Hogan, Kelly A; Sampson, Natalie et al. (2018) Examining Joint Effects of Air Pollution Exposure and Social Determinants of Health in Defining ""At-Risk"" Populations Under the Clean Air Act: Susceptibility of Pregnant Women to Hypertensive Disorders of Pregnancy. World Med Health Policy 10:7-54
Park, Hae-Ryung; Harris, Sean M; Boldenow, Erica et al. (2018) Group B streptococcus activates transcriptomic pathways related to premature birth in human extraplacental membranes in vitro. Biol Reprod 98:396-407
Torres, Norma I; Yu, Xue; Padilla, Ingrid Y et al. (2018) The influence of hydrogeological and anthropogenic variables on phthalate contamination in eogenetic karst groundwater systems. Environ Pollut 237:298-307
Ferguson, Kelly K; Yu, Youfei; Cantonwine, David E et al. (2018) Foetal ultrasound measurement imputations based on growth curves versus multiple imputation chained equation (MICE). Paediatr Perinat Epidemiol 32:469-473
Boss, Jonathan; Zhai, Jingyi; Aung, Max T et al. (2018) Associations between mixtures of urinary phthalate metabolites with gestational age at delivery: a time to event analysis using summative phthalate risk scores. Environ Health 17:56

Showing the most recent 10 out of 163 publications