Adolescents with alcohol related problems are increasingly being recognized as a heterogeneous population, with multiple developmental trajectories leading to alcohol use disorders. Psychologically traumatic experiences are among the environmental factors often postulated to contribute to the development of adolescent alcohol use disorders. In our current investigation, a substantially higher proportion of adolescents with alcohol use disorders than community controls have experienced trauma and posttraumatic stress disorder (PTSD). This study s designed to test the hypothesis that PTSD symptoms and abnormalities in biological stress response systems comprise the mechanisms through which trauma adversely influences the development and course of alcohol use disorders. This hypothesis will be tested through three integrated studies; (1) a cross- sectional stud utilizing a neuroendocrine laboratory assessment and structured equation modeling to examine the relationships among trauma, indices of catecholamine system and hypothalamic-pituitary-adrenal axis activities, pTSD symptoms, and alcohol related problems; (2) a prospective study determining the impact of trauma and PTSD symptoms on short-term and long-term outcome for adolescents with alcohol use disorders; and, (3) a prospective study examining whether or not trauma and PTSD symptoms predict alcohol-related problems in adolescents without alcohol use disorders at baseline. The results of this study will determine the mechanisms governing the impact of trauma on alcohol use disorders in adolescents, will identify specific areas important for relapse prevention and will lead to the development of specific methods for identifying adolescents at high risk for alcohol use disorders for preventative interventions.
| Altszuler, Amy R; Page, Timothy F; Gnagy, Elizabeth M et al. (2016) Financial Dependence of Young Adults with Childhood ADHD. J Abnorm Child Psychol 44:1217-29 |
| Molina, Brooke S G; Gnagy, Elizabeth M; Joseph, Heather M et al. (2016) Antisocial Alcoholism in Parents of Adolescents and Young Adults With Childhood ADHD. J Atten Disord : |
| Babinski, Dara E; Pelham Jr, William E; Molina, Brooke S G et al. (2016) Maternal ADHD, Parenting, and Psychopathology Among Mothers of Adolescents With ADHD. J Atten Disord 20:458-68 |
| Kuriyan, Aparajita B; Pelham Jr, William E; Molina, Brooke S G et al. (2014) Concordance between parent and physician medication histories for children and adolescents with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol 24:269-74 |
| Babinski, Dara E; Sibley, Margaret H; Ross, J Megan et al. (2013) The effects of single versus mixed gender treatment for adolescent girls with ADHD. J Clin Child Adolesc Psychol 42:243-50 |
| Kuriyan, Aparajita B; Pelham Jr, William E; Molina, Brooke S G et al. (2013) Young adult educational and vocational outcomes of children diagnosed with ADHD. J Abnorm Child Psychol 41:27-41 |
| Sibley, Margaret H; Pelham, William E; Molina, Brooke S G et al. (2012) When diagnosing ADHD in young adults emphasize informant reports, DSM items, and impairment. J Consult Clin Psychol 80:1052-1061 |
| Sibley, Margaret H; Pelham, William E; Molina, Brooke S G et al. (2012) Diagnosing ADHD in adolescence. J Consult Clin Psychol 80:139-150 |
| Sibley, Margaret H; Pelham, William E; Molina, Brooke S G et al. (2011) The delinquency outcomes of boys with ADHD with and without comorbidity. J Abnorm Child Psychol 39:21-32 |
| Babinski, Dara E; Pelham Jr, William E; Molina, Brooke S G et al. (2011) Late adolescent and young adult outcomes of girls diagnosed with ADHD in childhood: an exploratory investigation. J Atten Disord 15:204-14 |
Showing the most recent 10 out of 113 publications
