The Animal Resource Laboratory is one of the Alcohol Research Center's Core Laboratories. The long-term goal of this Core is to serve as a central facility through which investigators can obtain well controlled and reproducible animal models, and receive training related to in vivo experimentation. It is envisaged that the Animal Core will enhance experimental productivity in alcohol research by achieving four specific aims: (1) to provide space, technical assistance (both surgical and experimental), equipment, and supplies for pre- an post-operative animal care; (2) to produce a well controlled and reproducible rodent model of chronic alcohol consumption; (3) to train and teach new investigators, students,and technicians the basic surgical and experimental skills required for whole animal research (educational component); and (4) to develop new models, techniques and experimental approaches when needed, and thereby broaden the surgical and experimental procedures available to investigators. The Animal Resource Core will be primarily used for investigators that have a Research Component, Pilot study supported by the Alcohol Research Center and/or a project supported by NIAAA that is related to the overall theme and objectives of the LSUMC Alcohol Research Center. By providing the above mentioned services the Animal Resources Laboratory will be able to substantially lower the expense of the proposed research both in time and money, reduce experimental variability and ensure animal welfare.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA009803-05
Application #
6267128
Study Section
Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
5
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Type
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Samuelson, Derrick R; de la Rua, Nicholas M; Charles, Tysheena P et al. (2016) Oral Immunization of Mice with Live Pneumocystis murina Protects against Pneumocystis Pneumonia. J Immunol 196:2655-65
Veazey, Ronald S; Amedee, Angela; Wang, Xiaolei et al. (2015) Chronic Binge Alcohol Administration Increases Intestinal T-Cell Proliferation and Turnover in Rhesus Macaques. Alcohol Clin Exp Res 39:1373-9
Katz, Paige S; Siggins, Robert W; Porretta, Connie et al. (2015) Chronic alcohol increases CD8+ T-cell immunosenescence in simian immunodeficiency virus-infected rhesus macaques. Alcohol 49:759-65
Armstrong, M L; LaPlante, A M; Altice, F L et al. (2015) Advancing Behavioral HIV Prevention: Adapting an Evidence-Based Intervention for People Living with HIV and Alcohol Use Disorders. AIDS Res Treat 2015:879052
Molina, Patricia E; Amedee, Angela M; Veazey, Ron et al. (2014) Chronic binge alcohol consumption does not diminish effectiveness of continuous antiretroviral suppression of viral load in simian immunodeficiency virus-infected macaques. Alcohol Clin Exp Res 38:2335-44
Brown, Armand O; Mann, Beth; Gao, Geli et al. (2014) Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function. PLoS Pathog 10:e1004383
Siggins, Robert W; Hossain, Fokhrul; Rehman, Tayyab et al. (2014) Cigarette Smoke Alters the Hematopoietic Stem Cell Niche. Med Sci (Basel) 2:37-50
Simon, Liz; LeCapitaine, Nicole; Berner, Paul et al. (2014) Chronic binge alcohol consumption alters myogenic gene expression and reduces in vitro myogenic differentiation potential of myoblasts from rhesus macaques. Am J Physiol Regul Integr Comp Physiol 306:R837-44
Molina, Patricia E; Gardner, Jason D; Souza-Smith, Flavia M et al. (2014) Alcohol abuse: critical pathophysiological processes and contribution to disease burden. Physiology (Bethesda) 29:203-15
Molina, Patricia E (2014) Alcohol binging exacerbates adipose tissue inflammation following burn injury. Alcohol Clin Exp Res 38:33-5

Showing the most recent 10 out of 56 publications