Administrative CoreThe Center for the Translational Neuroscience of Alcoholism (CTNA) places a high priority onmaintaining an efficient flow of information in order to promote the safe and successful completion ofproposed studies, to support the initiation of novel pilot studies, to facilitate the career development oftrainees and junior faculty affiliated with the Center, and to promote the dissemination of researchadvances. However, the CTNA views its mission as 'translational' in that it places a high priority on theinterplay between basic and clinical neuroscience. Thus, its administrative, monitoring, and educationalcomponents include representation from basic and clinical neuroscience and these components arecharged with preserving the integrity of the translational mission.The Administrative Core provides for the centralized organizational functions of the Center for theTranslational Neuroscience of Alcoholism (CTNA). These functions include 1) the central executivefunction of the Center (Director, Executive Committee), 2) the management and analysis of datacollected within the Center (Informatics and Biostatistics Section), 3) data safety monitoring (Data SafetyMonitoring Board), 4) educational functions (Education Committee), 5) and external ongoing review ofthe scientific merit of CTNA activities (Scientific Advisory Board).

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA012870-08
Application #
7622271
Study Section
Special Emphasis Panel (ZAA1-HH (60))
Project Start
2008-06-01
Project End
2011-05-31
Budget Start
2008-06-01
Budget End
2009-05-31
Support Year
8
Fiscal Year
2008
Total Cost
$631,910
Indirect Cost
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
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Polimanti, Renato; Kayser, Manfred H; Gelernter, Joel (2018) Local adaptation in European populations affected the genetics of psychiatric disorders and behavioral traits. Genome Med 10:24
Polimanti, R; Kaufman, J; Zhao, H et al. (2018) A genome-wide gene-by-trauma interaction study of alcohol misuse in two independent cohorts identifies PRKG1 as a risk locus. Mol Psychiatry 23:154-160
Polimanti, R; Kaufman, J; Zhao, H et al. (2018) Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers. Acta Psychiatr Scand 137:148-156
Ide, Jaime S; Zhornitsky, Simon; Chao, Herta H et al. (2018) Thalamic Cortical Error-Related Responses in Adult Social Drinkers: Sex Differences and Problem Alcohol Use. Biol Psychiatry Cogn Neurosci Neuroimaging 3:868-877
D'Souza, Deepak Cyril; Carson, Richard E; Driesen, Naomi et al. (2018) Dose-Related Target Occupancy and Effects on Circuitry, Behavior, and Neuroplasticity of the Glycine Transporter-1 Inhibitor PF-03463275 in Healthy and Schizophrenia Subjects. Biol Psychiatry 84:413-421
Polimanti, Renato; Gelernter, Joel; Stein, Dan J (2018) Genetically determined schizophrenia is not associated with impaired glucose homeostasis. Schizophr Res 195:286-289
Foster, Dawn W; Ye, Feifei; O'Malley, Stephanie S et al. (2018) Longitudinal Associations Between Alcohol-Related Cognitions and Use in African American and European American Adolescent Girls. Alcohol Clin Exp Res 42:962-971
Polimanti, Renato; Gelernter, Joel (2018) ADH1B: From alcoholism, natural selection, and cancer to the human phenome. Am J Med Genet B Neuropsychiatr Genet 177:113-125
Zhou, Hang; Cheng, Zhongshan; Bass, Nicholas et al. (2018) Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression. Transl Psychiatry 8:208

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