Abstract

The Biostatistics Core has four major responsibilities: 1) to provide statistical design and analysis consultation services to ADRC investigators; 2) to prepare the ADRC database for submission to the Alzheimer's Disease Data Coordinating Center; 3) to coordinate the entry, quality control and management of data generated by the Clinical and Neuropathology cores; and 4) to educate investigators trainees and junior facility in the principles and use of statistical analysis methodologies. Statistical consultation ranges from power analysis and the conduct of complex multivariate modeling. Data management and information distribution will be facilitated by the continued development of high-e4nd relational database systems accessible through a private Intranet.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
3P50AG005131-17S1
Application #
6398523
Study Section
Project Start
2000-06-01
Project End
2001-03-31
Budget Start
Budget End
Support Year
17
Fiscal Year
2000
Total Cost
Indirect Cost

  Institution

Name
University of California San Diego
Department
Type
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Hanfelt, John J; Peng, Limin; Goldstein, Felicia C et al. (2018) Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center. Neurobiol Dis 117:62-71
Zhou, Zilu; Wang, Weixin; Wang, Li-San et al. (2018) Integrative DNA copy number detection and genotyping from sequencing and array-based platforms. Bioinformatics 34:2349-2355
Burke, Shanna L; Hu, Tianyan; Fava, Nicole M et al. (2018) Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. J Women Aging :1-25
Wang, Qi; Guo, Lei; Thompson, Paul M et al. (2018) The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1. J Alzheimers Dis 64:149-169
Sundermann, Erin E; Tran, My; Maki, Pauline M et al. (2018) Sex differences in the association between apolipoprotein E ?4 allele and Alzheimer's disease markers. Alzheimers Dement (Amst) 10:438-447
Besser, Lilah; Kukull, Walter; Knopman, David S et al. (2018) Version 3 of the National Alzheimer's Coordinating Center's Uniform Data Set. Alzheimer Dis Assoc Disord 32:351-358
Edmonds, Emily C; Weigand, Alexandra J; Thomas, Kelsey R et al. (2018) Increasing Inaccuracy of Self-Reported Subjective Cognitive Complaints Over 24 Months in Empirically Derived Subtypes of Mild Cognitive Impairment. J Int Neuropsychol Soc 24:842-853
Graves, Lisa V; Van Etten, Emily J; Holden, Heather M et al. (2018) Refining CVLT-II recognition discriminability indices to enhance the characterization of recognition memory changes in healthy aging. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 25:767-782
Crum, Jana; Wilson, Jeffrey; Sabbagh, Marwan (2018) Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia? Alzheimers Res Ther 10:104
Wang, Tingyan; Qiu, Robin G; Yu, Ming (2018) Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks. Sci Rep 8:9161

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