The primary objective of this Core is to provide biostatistical, epidemiological, and statistical genetic consultation and computing services to the Cores and Projects of the University of Washington Alzheimer's Disease Research Center (ADRC).
Specific aims are:
SPECIFIC AIM 1. To continue to provide the statistical, data base, and computer services that have been provided over the last five years;
SPECIFIC AIM 2. To provide statistical genetics expertise for all projects and cores;
SPECIFIC AIM 3. To give epidemiological guidance to projects and cores;
SPECIFIC AIM 4. To develop a proactive approach for service to projects and cores;
and SPECIFIC AIM 5. To develop and apply appropriate statistical methodologies for analytical problems arising out of research projects cores. Core systems analysts and programmers: 1) maintain computer hardware and software for data base and analytical needs of all Cores and Projects, 2) maintain large scale longitudinal data bases for the Clinical (C1) and Satellite (C2) Cores, and 3) provide consultation on computer hardware and software, and provide programming services as needed to all Cores and Projects. Core biostatisticians, epidemiologist, and statistical geneticists are available to all Cores and Projects for consultation regarding the design, analysis, and interpretation of data, including the development of new analytical methodologies as required and the authoring and coauthoring manuscripts analyzing ADRC data and describing said methodologies.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005136-14
Application #
6234062
Study Section
Project Start
1997-05-01
Project End
1998-04-30
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
14
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Crum, Jana; Wilson, Jeffrey; Sabbagh, Marwan (2018) Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia? Alzheimers Res Ther 10:104
Turk, Katherine W; Flanagan, Margaret E; Josephson, Samuel et al. (2018) Psychosis in Spinocerebellar Ataxias: a Case Series and Study of Tyrosine Hydroxylase in Substantia Nigra. Cerebellum 17:143-151
Petyuk, Vladislav A; Chang, Rui; Ramirez-Restrepo, Manuel et al. (2018) The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target. Brain 141:2721-2739
Bharadwaj, Rajnish; Cimino, Patrick J; Flanagan, Margaret E et al. (2018) Application of the condensed protocol for the NIA-AA guidelines for the neuropathological assessment of Alzheimer's disease in an academic clinical practice. Histopathology 72:433-440
Burke, Shanna L; Cadet, Tamara; Maddux, Marlaina (2018) Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults. J Natl Med Assoc 110:314-325
Alosco, Michael L; Sugarman, Michael A; Besser, Lilah M et al. (2018) A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. J Alzheimers Dis 63:1347-1360
Kamara, Dennis M; Gangishetti, Umesh; Gearing, Marla et al. (2018) Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. J Alzheimers Dis 62:1815-1826
Brent, Robert J (2018) Estimating the monetary benefits of medicare eligibility for reducing the symptoms of dementia. Appl Econ 50:6327-6340
Tulloch, Jessica; Leong, Lesley; Chen, Sunny et al. (2018) APOE DNA methylation is altered in Lewy body dementia. Alzheimers Dement 14:889-894
Deming, Yuetiva; Dumitrescu, Logan; Barnes, Lisa L et al. (2018) Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol 136:857-872

Showing the most recent 10 out of 753 publications