The primary objective of this Core is to provide biostatistical, epidemiological, and statistical genetic consultation and computing services to the Cores and Projects of the University of Washington Alzheimer's Disease Research Center (ADRC).
Specific aims are:
SPECIFIC AIM 1. To continue to provide the statistical, data base, and computer services that have been provided over the last five years;
SPECIFIC AIM 2. To provide statistical genetics expertise for all projects and cores;
SPECIFIC AIM 3. To give epidemiological guidance to projects and cores;
SPECIFIC AIM 4. To develop a proactive approach for service to projects and cores;
and SPECIFIC AIM 5. To develop and apply appropriate statistical methodologies for analytical problems arising out of research projects cores. Core systems analysts and programmers: 1) maintain computer hardware and software for data base and analytical needs of all Cores and Projects, 2) maintain large scale longitudinal data bases for the Clinical (C1) and Satellite (C2) Cores, and 3) provide consultation on computer hardware and software, and provide programming services as needed to all Cores and Projects. Core biostatisticians, epidemiologist, and statistical geneticists are available to all Cores and Projects for consultation regarding the design, analysis, and interpretation of data, including the development of new analytical methodologies as required and the authoring and coauthoring manuscripts analyzing ADRC data and describing said methodologies.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
3P50AG005136-16S1
Application #
6216968
Study Section
Project Start
1999-08-15
Project End
2000-04-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
16
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
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Schaffert, Jeff; LoBue, Christian; White, Charles L et al. (2018) Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease. Neuropsychology 32:410-416
Brenowitz, Willa D; Han, Fang; Kukull, Walter A et al. (2018) Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults. Neurobiol Aging 62:64-71
Tulloch, Jessica; Leong, Lesley; Thomson, Zachary et al. (2018) Glia-specific APOE epigenetic changes in the Alzheimer's disease brain. Brain Res 1698:179-186

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