Abstract

Public Health Relevance

Alzheimer's disease and other dementias are growing as our population ages. The development of new treatments for these challenging diseases is critical to the health of our population. The rationale for these studies is derived from growing evidence that insulin contributes to multiple brain functions, and that insulin dysregulation can contribute to Alzheimer's disease. A better understanding of the role insulin plays in cognition may lead to new treatments and strategies for preventing dementia or delaying its onset.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005136-29
Application #
8441079
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
Project End
Budget Start
2012-05-01
Budget End
2013-04-30
Support Year
29
Fiscal Year
2012
Total Cost
$190,024
Indirect Cost
$30,797

  Institution

Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Ramsey, Christine M; Gnjidic, Danijela; Agogo, George O et al. (2018) Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimers Dement (N Y) 4:1-10
Goins, R Turner; Schure, Mark; Jensen, Paul N et al. (2018) Lower body functioning and correlates among older American Indians: The Cerebrovascular Disease and Its Consequences in American Indians Study. BMC Geriatr 18:6
Iverson, Grant L; Keene, C Dirk; Perry, George et al. (2018) The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features. J Alzheimers Dis 61:17-28
Kirson, Noam Y; Scott Andrews, J; Desai, Urvi et al. (2018) Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease. J Alzheimers Dis 61:295-307
Hadjichrysanthou, Christoforos; McRae-McKee, Kevin; Evans, Stephanie et al. (2018) Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies. J Alzheimers Dis 66:587-600
Flanagan, Margaret E; Keene, Christopher Dirk; Louis, David N et al. (2018) Localized crystal-storing histiocytosis of the posterior fossa. Neuropathology 38:529-534
Rane, Swati; Koh, Natalie; Boord, Peter et al. (2018) Quantitative cerebrovascular pathology in a community-based cohort of older adults. Neurobiol Aging 65:77-85
Dams-O'Connor, Kristen; Sy, Karla Therese L; Landau, Alexandra et al. (2018) The Feasibility of Telephone-Administered Cognitive Testing in Individuals 1 and 2 Years after Inpatient Rehabilitation for Traumatic Brain Injury. J Neurotrauma 35:1138-1145
Weintraub, Sandra; Besser, Lilah; Dodge, Hiroko H et al. (2018) Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord 32:10-17
Hanfelt, John J; Peng, Limin; Goldstein, Felicia C et al. (2018) Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center. Neurobiol Dis 117:62-71

Showing the most recent 10 out of 753 publications