Abstract

Public Health Relevance

Participants in this long term study may have experienced subtle changes in memory and cognitive resources associated with early pathological indices. Results will inform theories of normal aging as well as models of the adverse effects of vascular changes in initial development of cognitive impairment. Results may suggest that reducing vascular risk may be key to reducing cognitive decline in older adults.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
2P50AG005142-26A1
Application #
8013750
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4 (J2))
Project Start
Project End
Budget Start
2010-07-01
Budget End
2012-03-31
Support Year
26
Fiscal Year
2010
Total Cost
$162,250
Indirect Cost

  Institution

Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089

  Publications

Nation, Daniel A (2018) Blood Pressure and Cerebral Blood Flow in Alzheimer Disease. Hypertension 72:68-69
Hadjichrysanthou, Christoforos; McRae-McKee, Kevin; Evans, Stephanie et al. (2018) Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies. J Alzheimers Dis 66:587-600
Hanfelt, John J; Peng, Limin; Goldstein, Felicia C et al. (2018) Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center. Neurobiol Dis 117:62-71
Burke, Shanna L; Hu, Tianyan; Fava, Nicole M et al. (2018) Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. J Women Aging :1-25
Wang, Qi; Guo, Lei; Thompson, Paul M et al. (2018) The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1. J Alzheimers Dis 64:149-169
Wang, Tingyan; Qiu, Robin G; Yu, Ming (2018) Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks. Sci Rep 8:9161
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487
Aydogan, Dogu Baran; Jacobs, Russell; Dulawa, Stephanie et al. (2018) When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity. Brain Struct Funct 223:2841-2858
Gahm, Jin Kyu; Shi, Yonggang; Alzheimer’s Disease Neuroimaging Initiative (2018) Riemannian metric optimization on surfaces (RMOS) for intrinsic brain mapping in the Laplace-Beltrami embedding space. Med Image Anal 46:189-201
Emrani, Sheina; Libon, David J; Lamar, Melissa et al. (2018) Assessing Working Memory in Mild Cognitive Impairment with Serial Order Recall. J Alzheimers Dis 61:917-928

Showing the most recent 10 out of 590 publications