The overall goals of the Training and Information Transfer Core (TITC) continue unchanged. These are: A) To increase awareness of and impart a body of knowledge about gerontology, neuroscience and AD in particular, and of the care of the DAT patient. B) To encourage more favorable attitudes toward and responsibility within our community for the care of DAT patients. C) To maintain and enhance our collaboration and cooperation with community agencies, resources, and healthcare practitioners who serve DAT patients and their families. D) To promote and improve research in Alzheimer's disease and to facilitate the exchange of knowledge among researchers both within and outside the Washington University community. E) To facilitate the recruitment efforts of the clinical core. We will continue to provide a broad spectrum of educational programs and materials for a diverse community of health care professionals, allied service professionals and community lay persons throughout the Midwest. We propose to expand our current activities by explicitly expanding Specific Aim A in two directions. These additional aims are: A1) To develop and increase educational programs for the African-American community (a currently underserved group) and to promote the advancement of African-American professionals in neuroscience, gerontology and AD- related training. A2) To consolidate and expand our outreach to the young student, further promoting knowledge of and positive attitudes toward the elderly and those suffering from neurological disorders such as AD, and to encourage neuroscience and aging research and care careers.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005681-13
Application #
5204525
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
La Joie, Renaud; Bejanin, Alexandre; Fagan, Anne M et al. (2018) Associations between [18F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample. Neurology 90:e282-e290
Kirson, Noam Y; Scott Andrews, J; Desai, Urvi et al. (2018) Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease. J Alzheimers Dis 61:295-307
Roe, Catherine M; Ances, Beau M; Head, Denise et al. (2018) Incident cognitive impairment: longitudinal changes in molecular, structural and cognitive biomarkers. Brain 141:3233-3248
Swarup, Vivek; Hinz, Flora I; Rexach, Jessica E et al. (2018) Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nat Med :
Day, Gregory S; Musiek, Erik S; Morris, John C (2018) Rapidly Progressive Dementia in the Outpatient Clinic: More Than Prions. Alzheimer Dis Assoc Disord 32:291-297
Ihara, Ryoko; Vincent, Benjamin D; Baxter, Michael R et al. (2018) Relative neuron loss in hippocampal sclerosis of aging and Alzheimer's disease. Ann Neurol 84:741-753
Bussy, Aurélie; Snider, B Joy; Coble, Dean et al. (2018) Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network. Neurobiol Aging 75:42-50
Sato, Chihiro; Barthélemy, Nicolas R; Mawuenyega, Kwasi G et al. (2018) Tau Kinetics in Neurons and the Human Central Nervous System. Neuron 97:1284-1298.e7
Sutphen, Courtney L; McCue, Lena; Herries, Elizabeth M et al. (2018) Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer's disease. Alzheimers Dement 14:869-879
Wang, Qi; Guo, Lei; Thompson, Paul M et al. (2018) The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1. J Alzheimers Dis 64:149-169

Showing the most recent 10 out of 952 publications