The purpose of this proposal is to describe the Memory and Aging Project Satellite which is designed to provide diagnosis and treatment of African American older adults in the St. Louis community. The primary goal of this program is to increase the participation of African American elderly in the ongoing activities of the Washington University Alzheimer's Disease Research Center. The major emphasis of the Satellite is to increase the recruitment and retention of African American elderly with DAT by the provision of supportive services which minimize the perceived barriers to participation among elderly blacks and their caregivers. A homebased model of service which links the ADRC with the St. Louis City Department of Health and the St. Louis Area Agency on Aging was developed in 1992. The diagnosis of DAT will be made by Marie Meisel R.N. using the usual clinical criteria defined by the Clinical Core. A family interview and functional assessment is also administered.The Clinical Core will provide the confirmation of the diagnosis , an estimated 20 African American subjects will be assessed by the Clinical Core each year. An additional 20 patients will be evaluated each year by the Barnes Neurology Clinic and added to the registry of African American elderly. The project will also document the effects of DAT on the families and community of African American elderly and assist in the development of ethnically sensitive and culturally appropriate community programs.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005681-15
Application #
6267367
Study Section
Project Start
1998-05-01
Project End
1999-04-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
15
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Vlassenko, Andrei G; Gordon, Brian A; Goyal, Manu S et al. (2018) Aerobic glycolysis and tau deposition in preclinical Alzheimer's disease. Neurobiol Aging 67:95-98
Javaherian, Kavon; Newman, Brianne M; Weng, Hua et al. (2018) Examining the Complicated Relationship Between Depressive Symptoms and Cognitive Impairment in Preclinical Alzheimer Disease. Alzheimer Dis Assoc Disord :
Wildburger, Norelle C; Gyngard, Frank; Guillermier, Christelle et al. (2018) Amyloid-? Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracer In Vivo and Exhibit Nanoscale Heterogeneity. Front Neurol 9:169
Lin, Ming; Gong, Pinghua; Yang, Tao et al. (2018) Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment. Alzheimer Dis Assoc Disord 32:18-27
Qiu, Shangran; Chang, Gary H; Panagia, Marcello et al. (2018) Fusion of deep learning models of MRI scans, Mini-Mental State Examination, and logical memory test enhances diagnosis of mild cognitive impairment. Alzheimers Dement (Amst) 10:737-749
Pehlivanova, Marieta; Wolf, Daniel H; Sotiras, Aristeidis et al. (2018) Diminished Cortical Thickness is Associated with Impulsive Choice in Adolescence. J Neurosci :
Gordon, Brian A; Blazey, Tyler M; Su, Yi et al. (2018) Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study. Lancet Neurol 17:241-250
Jansen, Willemijn J; Ossenkoppele, Rik; Tijms, Betty M et al. (2018) Association of Cerebral Amyloid-? Aggregation With Cognitive Functioning in Persons Without Dementia. JAMA Psychiatry 75:84-95
Allison, Samantha; Babulal, Ganesh M; Stout, Sarah H et al. (2018) Alzheimer Disease Biomarkers and Driving in Clinically Normal Older Adults: Role of Spatial Navigation Abilities. Alzheimer Dis Assoc Disord 32:101-106
Stout, Sarah H; Babulal, Ganesh M; Ma, Chunyu et al. (2018) Driving cessation over a 24-year period: Dementia severity and cerebrospinal fluid biomarkers. Alzheimers Dement 14:610-616

Showing the most recent 10 out of 952 publications