Six of the individual research projects in this SCOR require the services of a Molecular Biology Core. The services include oligonucleotide synthesis and purification, plasmid preparations, and DNA amplification.

Project Start
1996-09-01
Project End
1998-08-31
Budget Start
Budget End
Support Year
10
Fiscal Year
1997
Total Cost
Indirect Cost
City
Dallas
State
TX
Country
United States
Zip Code
75390
Rosloniec, Edward F; Whittington, Karen B; He, Xiaowen et al. (2004) Collagen-induced arthritis mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401). Am J Med Sci 327:169-79
Hayashida, K; Nanki, T; Girschick, H et al. (2001) Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8. Arthritis Res 3:118-26
Nanki, T; Lipsky, P E (2001) Stimulation of T-Cell activation by CXCL12/stromal cell derived factor-1 involves a G-protein mediated signaling pathway. Cell Immunol 214:145-54
Nanki, T; Lipsky, P E (2000) Cutting edge: stromal cell-derived factor-1 is a costimulator for CD4+ T cell activation. J Immunol 164:5010-4
Nanki, T; Lipsky, P E (2000) Lack of correlation between chemokine receptor and T(h)1/T(h)2 cytokine expression by individual memory T cells. Int Immunol 12:1659-67
Hayashida, K; Shimaoka, Y; Ochi, T et al. (2000) Rheumatoid arthritis synovial stromal cells inhibit apoptosis and up-regulate Bcl-xL expression by B cells in a CD49/CD29-CD106-dependent mechanism. J Immunol 164:1110-6
He, X; Stuart, J M (1999) Prostaglandin E2 selectively inhibits human CD4+ T cells secreting low amounts of both IL-2 and IL-4. J Immunol 163:6173-9
Brezinschek, R I; Oppenheimer-Marks, N; Lipsky, P E (1999) Activated T cells acquire endothelial cell surface determinants during transendothelial migration. J Immunol 162:1677-84
Schulze-Koops, H; Lipsky, P E; Davis, L S (1998) Human memory T cell differentiation into Th2-like effector cells is dependent on IL-4 and CD28 stimulation and inhibited by TCR ligation. Eur J Immunol 28:2517-29
Davis, L S; Lipsky, P E (1998) Disordered differentiation of memory T cells in rheumatoid arthritis. Rev Rhum Engl Ed 65:291-6

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