Abstract

Core B: Biochemistry The Biochemistry Core provides specimen processing and chemical determinations on serum, urine, stool, and dietary specimens. It also is responsible for acquiring stool, urine, and blood specimens for mailing to outside reference laboratories. Assays routinely carried out include calcium, phosphorus, protein, creatinine, hydroxyproline, FSH, 25- hydroxyvitamin D, 1,25 dihydroxyvitamin D, bone Gla protein, estradiol, as well as radiochemical determinations of 45Ca and 47Ca. As a general biochemistry laboratory, this core laboratory is equipped to provide a number of other chemical determinations, such as fecal fat, serum strontium, and certain other tests, including urine sodium and potassium.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Specialized Center (P50)
Project #
5P50AR039221-10
Application #
5206220
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Recker, Robert; Lappe, Joan; Davies, K Michael et al. (2004) Bone remodeling increases substantially in the years after menopause and remains increased in older osteoporosis patients. J Bone Miner Res 19:1628-33
Paschalis, E P; Recker, R; DiCarlo, E et al. (2003) Distribution of collagen cross-links in normal human trabecular bone. J Bone Miner Res 18:1942-6
Heaney, Robert P (2003) Normalizing calcium intake: projected population effects for body weight. J Nutr 133:268S-270S
Samnegard, E; Akhter, M P; Recker, R R (2001) Maintenance of vertebral body bone mass and strength created by human parathyroid hormone treatment in ovariectomized rats. Bone 28:414-22
Iwaniec, U T; Samnegard, E; Cullen, D M et al. (2001) Maintenance of cancellous bone in ovariectomized, human parathyroid hormone [hPTH(1-84)]-treated rats by estrogen, risedronate, or reduced hPTH. Bone 29:352-60
Cullen, D M; Smith, R T; Akhter, M P (2001) Bone-loading response varies with strain magnitude and cycle number. J Appl Physiol 91:1971-6
Davies, K M; Heaney, R P; Recker, R R et al. (2001) Hormones, weight change and menopause. Int J Obes Relat Metab Disord 25:874-9
Samnegard, E; Iwaniec, U T; Cullen, D M et al. (2001) Maintenance of cortical bone in human parathyroid hormone(1-84)-treated ovariectomized rats. Bone 28:251-60
Samnegard, E; Cullen, D M; Akhter, M P et al. (2001) No effect of verapamil on the local bone response to in vivo mechanical loading. J Orthop Res 19:328-36
Cullen, D M; Smith, R T; Akhter, M P (2000) Time course for bone formation with long-term external mechanical loading. J Appl Physiol 88:1943-8

Showing the most recent 10 out of 57 publications