This program will be directed by Gail Mahady (Res. Asst. Prof., Ph.D. 1991 in pharmacognosy, UIC) and Jan Engle (Clinical Assoc. Prof. Of Pharmacy, D. Pharm. 1985, UIC). Its major aim is to strengthen graduate and postgraduate training programs in pharmacognosy in order to provide a significant number of scientists able to address issues such as the quality, safety, and efficacy of botanical supplements. Curricula will be developed, and interactive Internet-based learning programs devised. Important biological, chemical, and pharmacological data will be collected from the literature for a number of medicinally important plants and assembled to provide a useful database. There will be an emphasis on botanicals relevant to women's health.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Specialized Center (P50)
Project #
5P50AT000155-04
Application #
6603606
Study Section
Special Emphasis Panel (ZRG1)
Project Start
2002-08-01
Project End
2003-07-31
Budget Start
Budget End
Support Year
4
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Simmler, Charlotte; Graham, James G; Chen, Shao-Nong et al. (2018) Integrated analytical assets aid botanical authenticity and adulteration management. Fitoterapia 129:401-414
Hajirahimkhan, Atieh; Mbachu, Obinna; Simmler, Charlotte et al. (2018) Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ER? Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication. J Nat Prod 81:966-975
Liu, Yang; Zhang, Yu; Chen, Shao-Nong et al. (2018) The influence of natural deep eutectic solvents on bioactive natural products: studying interactions between a hydrogel model and Schisandra chinensis metabolites. Fitoterapia 127:212-219
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Dunlap, Tareisha L; Howell, Caitlin E; Mukand, Nita et al. (2017) Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism. Chem Res Toxicol 30:2084-2092
Keiler, Annekathrin M; Macejova, Dana; Dietz, Birgit M et al. (2017) Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats. J Steroid Biochem Mol Biol 174:234-241
Huang, Lingyi; Nikolic, Dejan; van Breemen, Richard B (2017) Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 409:6937-6948
AbouZid, Sameh F; Ahmed, Hayam S; Moawad, Abeer S et al. (2017) Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations. Fitoterapia 119:175-184
Simmler, Charlotte; Lankin, David C; Nikoli?, Dejan et al. (2017) Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A. Fitoterapia 121:6-15

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