The Administration and Development Core will be essential to the overall coordination and synergy of the three research Projects and 2 Cores. A major function of the Core will be to facilitate the exchange of data, information, and ideas between the 35 or more Botanical Research Center (BRC) scientists and internal and external collaborators. Meetings of the Internal Steering Committee will be held on a monthly basis. This Core will also organize biannual, day-long meetings with the External Advisory Committee, an exercise that has yielded valuable feedback during the first funding cycle. Previous experience has shown that frequent communications between and meetings among investigators are crucial to achieving the overall mission and scientific success of the BRC. This Core also serves as an initial contact point for inquiries from the University, the National Institutes of Health, the lay public, healthcare professionals, and the press. It disseminates general information to these groups and will also conduct targeted literature reviews for BRC members.
The specific aims of this Core are to 1.) coordinate formal interactions between Projects and Cores, coordinate formal interactions between the Botanical Research Center and external entities, industrial, academic, and advisory 3.) provide general administrative support, 4.) provide biostatistics support for the basic and clinical research teams, 5.) administer the Pilot Project Program, and 6.) administer the Training and Career Development Program. A main goal of both the Pilot Project Program and the Training and Career Development Program will be to foster the research programs of junior investigators - both trainee and faculty - and encourage them to apply for external sponsored research funding. All components of the Center and the investigators therein will benefit from the services of this Core. This Core will continuously interact with and seek guidance from each of the Projects and Cores in order to optimize its support of and service to the other BRC components.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Specialized Center (P50)
Project #
5P50AT000155-10
Application #
7897710
Study Section
Special Emphasis Panel (ZAT1)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
10
Fiscal Year
2009
Total Cost
$92,004
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612
Hajirahimkhan, Atieh; Mbachu, Obinna; Simmler, Charlotte et al. (2018) Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ER? Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication. J Nat Prod 81:966-975
Liu, Yang; Zhang, Yu; Chen, Shao-Nong et al. (2018) The influence of natural deep eutectic solvents on bioactive natural products: studying interactions between a hydrogel model and Schisandra chinensis metabolites. Fitoterapia 127:212-219
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Rue, Emily A; Rush, Michael D; van Breemen, Richard B (2018) Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry. Phytochem Rev 17:1-16
Simmler, Charlotte; Graham, James G; Chen, Shao-Nong et al. (2018) Integrated analytical assets aid botanical authenticity and adulteration management. Fitoterapia 129:401-414
Dunlap, Tareisha L; Howell, Caitlin E; Mukand, Nita et al. (2017) Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism. Chem Res Toxicol 30:2084-2092
Keiler, Annekathrin M; Macejova, Dana; Dietz, Birgit M et al. (2017) Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats. J Steroid Biochem Mol Biol 174:234-241
Huang, Lingyi; Nikolic, Dejan; van Breemen, Richard B (2017) Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 409:6937-6948
AbouZid, Sameh F; Ahmed, Hayam S; Moawad, Abeer S et al. (2017) Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations. Fitoterapia 119:175-184
Simmler, Charlotte; Lankin, David C; Nikoli?, Dejan et al. (2017) Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A. Fitoterapia 121:6-15

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