There is an urgent need to train investigators who have the quality and breadth of experience necessary to conduct transdiscipinary tobacco use research. Although there is no agreed upon model for training transdisciplinary scientists, important components include a rich institutional environment (e.g., physical proximity among trainees, mentors, and collaborators from diverse disciplines), a transdisciplinary curriculum (e.g., opportunities to acquire core attitudes, values, and beliefs, knowledge in scientific approaches, and methodological expertise), and competencies (i.e., attitudes, knowledge, and skills). Essential attitudes, knowledge, and skills are gained through course work, seminars and workshops, mentoring relationships, research experience, interactive groups, and a supportive institutional environment. The overall goal of the University of Pennsylvania's Transdisciplinary Tobacco Use Research Center (TTURC) Training Core is to provide transdisciplinary training in tobacco use research and practice for post-doctoral fellows and medical residents. The primary specific aims are: (1) To recruit and train 3 post-doctoral fellows who are dedicated to developing a career in transdisciplinary tobacco use research. This will be accomplished by providing a co-mentored training experience (with each mentor from a different discipline), as well as formal didactic experiences and independent (mentored) research; (2) To integrate training in tobacco use research in existing fellowship programs at PENN. This will be done via workshops and didactic experiences supplemented by individual mentored research experiences; and (3) To facilitate cross-training in tobacco research of current faculty at PENN through seminar series, tobacco affinity groups, and the submission of manuscripts, pilot projects, and grant applications. A secondary aim will be to integrate didactic coursework in tobacco use research into the required curricula for medical residents at PENN (internal medicine, family medicine, and psychiatry) in an effort to affect tobacco research as well as clinical practice.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA084718-11
Application #
7668743
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2008-09-30
Budget End
2009-09-29
Support Year
11
Fiscal Year
2008
Total Cost
$142,119
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Hsu, Ping-Ching; Lan, Renny S; Brasky, Theodore M et al. (2017) Metabolomic profiles of current cigarette smokers. Mol Carcinog 56:594-606
Hsu, Ping-Ching; Lan, Renny S; Brasky, Theodore M et al. (2017) Menthol Smokers: Metabolomic Profiling and Smoking Behavior. Cancer Epidemiol Biomarkers Prev 26:51-60
Weng, Daniel Y; Chen, Jinguo; Taslim, Cenny et al. (2016) Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers. Mol Carcinog 55:1424-37
Song, Min-Ae; Marian, Catalin; Brasky, Theodore M et al. (2016) Chemical and toxicological characteristics of conventional and low-TSNA moist snuff tobacco products. Toxicol Lett 245:68-77
Schnoll, Robert A; Goelz, Patricia M; Veluz-Wilkins, Anna et al. (2015) Long-term nicotine replacement therapy: a randomized clinical trial. JAMA Intern Med 175:504-11
David, Sean P; Strong, David R; Leventhal, Adam M et al. (2013) Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction 108:2202-11
Bough, K J; Lerman, C; Rose, J E et al. (2013) Biomarkers for smoking cessation. Clin Pharmacol Ther 93:526-38
Perkins, Kenneth A; Parzynski, Craig; Mercincavage, Melissa et al. (2012) Is self-efficacy for smoking abstinence a cause of, or a reflection on, smoking behavior change? Exp Clin Psychopharmacol 20:56-62
Conklin, Cynthia A; Parzynski, Craig S; Salkeld, Ronald P et al. (2012) Cue reactivity as a predictor of successful abstinence initiation among adult smokers. Exp Clin Psychopharmacol 20:473-8
Featherstone, Robert E; Phillips, Jennifer M; Thieu, Tony et al. (2012) Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials. PLoS One 7:e39775

Showing the most recent 10 out of 148 publications