The Biostatistics Core provides statistical collaboration and data management support for each of theSPORE projects, the developmental projects, and the Cores. Each of the projects presented in thisapplication reflects input from members of the Biostatistics Core on study design and analysis plan. TheBiostatistics Core will provide statistical support across many different fields, including statistical genetics,epidemiological studies, basic sciences including gene array, and clinical trials. This comprehensive natureof the Biostatistics Core assures each SPORE investigator access to statistical expertise that includescollaborative development of study designs and analysis plans, state of the an' data analysis andinterpretation, data management resources, and abstract and manuscript preparation. The Biostatistics Corealso provides a mechanism for the management and integration, of both existing and newly collected datathrough consistent and compatible data handling. Areas of support include database development, data formdevelopment and processing, quality control, data collection and entry, and data archiving. This Corecomplements and assists the efforts of other Cores such as the Clinical and Biospecimen Cores by providingdata management expertise and experience with tissue registries such as the Radical Prostatectomydatabase. The Biostatistics Core builds upon the innovative and time-tested procedures and systemsdeveloped by one of the largest statistical groups in the country whose members have collaborated on morethan 10,000 clinical and basic science research studies since 1966.
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