Innovative translational research in leukemia is critically dependent on the availability of funding for pilotprojects. The Leukemia SPORE Developmental Research Program (DRP) will be a source of seed fundingwith the following goals: 1) encourage and explore innovative translational research ideas which focus onleukemia research; and 2) encourage successful researchers working in other fields to focus their expertisetoward the development of innovative translational projects in leukemia research. Both laboratory andclinical research projects are eligible for funding, provided that they are translational in nature. The purposeof the SPORE Developmental Research Program is to develop translational research projects that shouldresult in clinically-testable hypotheses aimed at improving prognosis for patients with leukemia. Support of$100,000 from the SPORE and $100,000 from matching institutional support as described in the letter ofInstitutional Commitment will provide a total of $200,000 per year available through the DevelopmentalResearch Program for approximately 4 to 5 projects (approximately $50,000 per project). Funding will beawarded for 1 year; with satisfactory review from the respective advisory committees and progress on theindividual projects' specific aims, the funding could be carried over for an additional year.The specific objectives of the Developmental Research Program are to:1. Publicize the availability of funds for pilot translational leukemia research studies. Identify throughthis mechanism innovative projects with significant potential for improving leukemia therapy andprognosis.2. Encourage collaborations of projects with scientists within the SPORE and outside the SPORE.3. Enhance the communication between the SPORE leaders and outside investigators to encouragethe development of innovative translational strategies in leukemia.4. Ensure program flexibility so that developmental projects that show promise can be: 1) funded fora second year; 2) encouraged to apply for peer-reviewed funding (i.e. R01); or 3) expanded tobecome full SPORE projects.Lay Description: Innovative translational research in leukemia is critically dependent on the availability offunding for pilot projects. The Leukemia SPORE Developmental Research Program will be a source of seedfunding with the following goals: 1) encourage and explore innovative translational research ideas whichfocus on leukemia research; and 2) encourage successful researchers working in other fields to focus theirexpertise toward the development of innovative translational projects in leukemia research
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