This developmental project will allow Dr. Blankenberg to develop tracers for PET imaging of angiogenesis with 18F-VEGF. He has developed a SPECT based approach for imaging angiogenesis and would like to now extend this to PET so that it may have greater resolution and sensitivity for clinical imaging of tumor angiogenesis. It will also allow him to gain more experience with development of PET tracers and PET imaging. This project has good synergy with Research Project #4 (Shawn Chen PI) since that project also develops PET tracers targeted against tumor angiogenesis, but uses RDG peptides.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA114747-04
Application #
7645577
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
4
Fiscal Year
2008
Total Cost
$80,728
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
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Hori, Sharon Seiko; Lutz, Amelie M; Paulmurugan, Ramasamy et al. (2017) A Model-Based Personalized Cancer Screening Strategy for Detecting Early-Stage Tumors Using Blood-Borne Biomarkers. Cancer Res 77:2570-2584
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