CORE A: AdministrationThe Administrative CORE A will oversee all administrative and scientific activities of the UPCI Skin CancerSPORE. Its responsibilities include the coordination of the internal scientific and clinical conduct and allfinancial, regulatory, and informatics components of the research that is planned and in progress. CORE Awill be responsible for internal and external communications regarding the weekly clinical-pathologyconferences of the SPORE investigators, and alternate-weekly clinical-scientific reviews of all protocols ofinvestigation for the SPORE, as well as the monthly data safety reviews. The Administrative CORE willoversee the clinical coordination, data management, and research tumor registry database that serves asannotation of all tissue bank specimens of the protocol-driven Immunological Monitoring and CellularProducts Laboratory Tissue Bank (CORE C), and the overarching Pathology Tissue Bank (CORE B) of thisSPORE. The Administrative CORE will be responsible for all communications with the external and internalScientific Advisory Boards, and NCI personnel. It will submit all reports upon SPORE activities, andcoordinate an annual retreat for the SPORE investigators, as well as the travel of SPORE investigators tothe annual NCI-sponsored SPORE meeting. The Administrative CORE will fund travel of selectedinvestigators to present their research results at scientific conferences, and assist investigators in thepreparation and submission of manuscripts for publication, maintaining the informatics associated with thisSPORE, including an annotated database expanded out of the tumor registry and linked to the protocolbasedand CORE B Tissue Bank resource, that include more than 7000 patients with melanoma and severalthousand tissue specimens collected upon protocols of investigation over the past 20 years. CORE A willmaintain a computerized library of pertinent references of the investigators, and will coordinate activities ofthe SPORE in relation to the UPCI and with the relevant Departmental Chairs responsible for thisInterdisciplinary Program to facilitate the research productivity and complementarities, and synergy within theinstitution an in relation to the other skin SPOREs and the UPCI, and Cooperative Groups. TheAdministrative CORE will interact with the Patient Representatives, and communicate with the NCI ProgramOffice, to ensure that the SPORE guidelines are adhered to and that the mandate for translational researchis accomplished efficiently and in a timely manner.
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