Specialized Resource C: Radiochemistry Core[1] Overview/AimsThe Radiochemistry Core provides ICMIC investigators with resources for studies using radiotracers labeledwith short-lived gamma-emitting radionuclides. Radiotracer methods such as single photon emissioncomputed tomography (SPECT) and positron emission tomography (PET) are expensive, technically complex,and require a combination of multidisciplinary resources that is hard for any individual investigator to establishor maintain. The Radiochemistry Core provides the cyclotron, radiochemistry laboratories equipped for handlingof high levels of radioactive materials, and expertise in synthetic and radiopharmaceutical chemistry andradiotracer characterization, both in vitro and in vivo.
The specific aims of the Radiochemistry Core are to: Design, develop, and provide short-lived gamma-emitting radiotracers for in vitro and in vivo experiments. Develop and carry out radioanalytical procedures for in vitro and in vivo characterization of radiotracers. Provide guidance and consultation on selection of radiotracer methodology to biological investigations. Provide mentoring and education in radiochemistry and radiotracer methods.
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