Abstract

The overall goal of this project is to test the hypothesis that Specific Language Impairment (SLI) is associated with deficits in acoustic processing. To this end, the mismatch negativity (MMN) of event-related potentials will be used to assess a variety of basic capacities associated with pre-attentive, automatic processing of acoustic events. These capacities include: 1. detection of changes in intensity, frequency and stimulus duration; 2. identifying features of acoustic stimuli that are constant while other features change; 3. determining that the order of two-tones pairs has changed; 4. determining that the serial order of three to five tones has changed; 5. forming an abstract rule as to the direction of change between the frequencies of two-tones pairs across a series of pairs (e.g., that they all rise in frequency from the first to the second tone), while the absolute frequencies of the tone pairs varies; 6. the duration of transient memory upon which the MMN relies. In addition, SLI and control subjects will receive training on the paradigm used in points 1-4 above which yields the poorest MMN to determine whether the MN will become larger in amplitude and/or shorter in latency.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Specialized Center (P50)
Project #
5P50DC000223-17
Application #
6324649
Study Section
Project Start
2000-07-01
Project End
2001-06-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
17
Fiscal Year
2000
Total Cost
$292,124
Indirect Cost

  Institution

Name
Albert Einstein College of Medicine
Department
Type
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461

  Publications

Schwartz, Richard G; Scheffler, Frances L V; Lopez, Karece (2013) Speech perception and lexical effects in specific language impairment. Clin Linguist Phon 27:339-54
Shafer, Valerie L; Schwartz, Richard G; Martin, Brett (2011) Evidence of deficient central speech processing in children with specific language impairment: the T-complex. Clin Neurophysiol 122:1137-55
Korczak, Peggy A; Stapells, David R (2010) Effects of various articulatory features of speech on cortical event-related potentials and behavioral measures of speech-sound processing. Ear Hear 31:491-504
Datta, Hia; Shafer, Valerie L; Morr, Mara L et al. (2010) Electrophysiological indices of discrimination of long-duration, phonetically similar vowels in children with typical and atypical language development. J Speech Lang Hear Res 53:757-77
Gravel, Judith S; Roberts, Joanne E; Roush, Jackson et al. (2006) Early otitis media with effusion, hearing loss, and auditory processes at school age. Ear Hear 27:353-68
Martin, Brett A; Stapells, David R (2005) Effects of low-pass noise masking on auditory event-related potentials to speech. Ear Hear 26:195-213
Oates, Peggy A; Kurtzberg, Diane; Stapells, David R (2002) Effects of sensorineural hearing loss on cortical event-related potential and behavioral measures of speech-sound processing. Ear Hear 23:399-415
Petinou, K C; Schwartz, R G; Gravel, J S et al. (2001) A preliminary account of phonological and morphophonological perception in young children with and without otitis media. Int J Lang Commun Disord 36:21-42
Gravel, J S; Wallace, I F (2000) Effects of otitis media with effusion on hearing in the first 3 years of life. J Speech Lang Hear Res 43:631-44
Gravel, J S; Wallace, I F (1998) Language, speech, and educational outcomes of otitis media. J Otolaryngol 27 Suppl 2:17-25

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