The aim of this component is to support the program of faculty development and to provide resources for additional oral health research by establishing a Core Oral Microbiology Laboratory in Meharry's School of Dentistry. The faculty development component of this application takes place in the context of a small research project which examines how children acquire S. mutans infection. The project requires that bacteria be cultured from plaque and saliva samples of mothers and children. Meharry investigators and the core laboratory staff will learn the techniques for doing this from collaborators at UAB, but for the study to be established in Nashville, Meharry needs a laboratory dedicated to oral microbiology. The Core Oral Laboratory will serve as that facility.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Specialized Center (P50)
Project #
3P50DE010595-06S1
Application #
2780138
Study Section
Project Start
Project End
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
6
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Meharry Medical College
Department
Type
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37208
Velez Edwards, Digna R; Tsosie, Krystal S; Williams, Scott M et al. (2014) Admixture mapping identifies a locus at 15q21.2-22.3 associated with keloid formation in African Americans. Hum Genet 133:1513-23
Smith, Joan C; Boone, Braden E; Opalenik, Susan R et al. (2008) Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways. J Invest Dermatol 128:1298-310
Dasanayake, Ananda P; Russell, Shirley; Boyd, Doryck et al. (2003) Preterm low birth weight and periodontal disease among African Americans. Dent Clin North Am 47:115-25, x-xi
Dasanayake, Ananda P; Caufield, Page W (2002) Prevalence of dental caries in Sri Lankan aboriginal Veddha children. Int Dent J 52:438-44
Zou, X; Caufield, P W; Li, Y et al. (2001) Complete nucleotide sequence and characterization of pUA140, a cryptic plasmid from Streptococcus mutans. Plasmid 46:77-85
Dasanayake, A P; Boyd, D; Madianos, P N et al. (2001) The association between Porphyromonas gingivalis-specific maternal serum IgG and low birth weight. J Periodontol 72:1491-7
Holt, R G; Raju, L (2000) Signal sequence and alanine-rich region of streptococcal protein antigen A of Streptococcus sobrinus can direct localization of alkaline phosphatase to the periplasm of Escherichia coli. FEMS Microbiol Lett 184:17-21