This core is an endocrinology core designed to measure two aspects of neuroendocrine responses that are known to impact on immune responses, and particularly to impact those immune responses involved in healing: the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic adrenal medullary (SAM) axis. HPA axis hormones to be assessed will be plasma and salivary cortisol, plasma ACTH, DHEA and its metabolites. SAM mediators measured will be plasma catecholamines epinephrine and norepinephrine. Other hormones measured will be pituitary growth hormone and IGF-1.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Specialized Center (P50)
Project #
5P50DE013749-05
Application #
6794794
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
2003
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Heffner, Kathi L; Kiecolt-Glaser, Janice K; Glaser, Ronald et al. (2014) Stress and anxiety effects on positive skin test responses in young adults with allergic rhinitis. Ann Allergy Asthma Immunol 113:13-8
Gouin, Jean-Philippe; Carter, C Sue; Pournajafi-Nazarloo, Hossein et al. (2012) Plasma vasopressin and interpersonal functioning. Biol Psychol 91:270-4
Gouin, Jean-Philippe; Kiecolt-Glaser, Janice K (2012) The impact of psychological stress on wound healing: methods and mechanisms. Crit Care Nurs Clin North Am 24:201-13
Gouin, Jean-Philippe; Carter, C Sue; Pournajafi-Nazarloo, Hossein et al. (2010) Marital behavior, oxytocin, vasopressin, and wound healing. Psychoneuroendocrinology 35:1082-90
Edwards, Kate M; Bosch, Jos A; Engeland, Christopher G et al. (2010) Elevated macrophage migration inhibitory factor (MIF) is associated with depressive symptoms, blunted cortisol reactivity to acute stress, and lowered morning cortisol. Brain Behav Immun 24:1202-8
Graham, Jennifer E; Glaser, Ronald; Loving, Timothy J et al. (2009) Cognitive word use during marital conflict and increases in proinflammatory cytokines. Health Psychol 28:621-30
Kiecolt-Glaser, Janice K; Heffner, Kathi L; Glaser, Ronald et al. (2009) How stress and anxiety can alter immediate and late phase skin test responses in allergic rhinitis. Psychoneuroendocrinology 34:670-80
Ariza, Maria-Eugenia; Glaser, Ronald; Kaumaya, Pravin T P et al. (2009) The EBV-encoded dUTPase activates NF-kappa B through the TLR2 and MyD88-dependent signaling pathway. J Immunol 182:851-9
Engeland, Christopher G; Sabzehei, Bahareh; Marucha, Phillip T (2009) Sex hormones and mucosal wound healing. Brain Behav Immun 23:629-35
Kostyk, S K; Popovich, P G; Stokes, B T et al. (2008) Robust axonal growth and a blunted macrophage response are associated with impaired functional recovery after spinal cord injury in the MRL/MpJ mouse. Neuroscience 156:498-514

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