Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Specialized Center (P50)
Project #
3P50DK048977-01S1
Application #
2149509
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1994-09-30
Project End
1999-08-31
Budget Start
1994-09-30
Budget End
1995-08-31
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Physiology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Guggino, William B (2004) The cystic fibrosis transmembrane regulator forms macromolecular complexes with PDZ domain scaffold proteins. Proc Am Thorac Soc 1:28-32
Ketchum, Christian J; Rajendrakumar, Garnepudi V; Maloney, Peter C (2004) Characterization of the adenosinetriphosphatase and transport activities of purified cystic fibrosis transmembrane conductance regulator. Biochemistry 43:1045-53
Cheng, Jie; Wang, Hua; Guggino, William B (2004) Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL. J Biol Chem 279:1892-8
Swiatecka-Urban, Agnieszka; Duhaime, Marc; Coutermarsh, Bonita et al. (2002) PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator. J Biol Chem 277:40099-105
Cheng, Jie; Moyer, Bryan D; Milewski, Michal et al. (2002) A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression. J Biol Chem 277:3520-9
Ketchum, Christian J; Yue, Hongwen; Alessi, Karen A et al. (2002) Intracellular cysteines of the cystic fibrosis transmembrane conductance regulator (CFTR) modulate channel gating. Cell Physiol Biochem 12:1-8
Norlin, A; Lu, L N; Guggino, S E et al. (2001) Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats. J Appl Physiol 90:1489-96
Ketchum, C J; Schmidt, W K; Rajendrakumar, G V et al. (2001) The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export. J Biol Chem 276:29007-11
Mickle, J E; Milewski, M I; Macek Jr, M et al. (2000) Effects of cystic fibrosis and congenital bilateral absence of the vas deferens-associated mutations on cystic fibrosis transmembrane conductance regulator-mediated regulation of separate channels. Am J Hum Genet 66:1485-95
Moyer, B D; Duhaime, M; Shaw, C et al. (2000) The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane. J Biol Chem 275:27069-74

Showing the most recent 10 out of 39 publications