Abstract

Modeling and Informatics (0.9 FTE) The modeling and informatics core has three missions (i) itprovide the electronic infrastructure for the CDP Web, CDP Wiki and its high performance computing andstorage systems (ii) it develops new informatics technologies and oversees development of SB-Pipeline (iii) ittrains CDP members in general on various types of software and assists with computer-intensive live-cellimaging. Jeremy Muhlich is primarily active as a programmer and was first author on the recently-submittedSB-Wiki paper, attesting to his high research productivity. Jay Copeland is involved in building andmaintaining infrastructure and is our primary contact with Harvard and MIT systems administrators. Jay alsoruns the AV services, Web sites, on-line registration etc for conferences and meetings. Finally, Jay is the firstpoint of contact in CDP for our software vendors and oversees all of its optical equipment (in addition to beinga systems administrator, Jay is an experienced microscopist).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
2P50GM068762-06
Application #
7695144
Study Section
Special Emphasis Panel (ZGM1-CBCB-4 (SB))
Project Start
2008-09-01
Project End
2013-08-31
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
6
Fiscal Year
2008
Total Cost
$178,993
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Jogalekar, Manasi P; Cooper, Leigh G; Serrano, Elba E (2017) Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma. Neurochem Res 42:2610-2624
Knight, V Bleu; Serrano, Elba E (2017) Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures. PeerJ 5:e2829
Jaqaman, Khuloud; Galbraith, James A; Davidson, Michael W et al. (2016) Changes in single-molecule integrin dynamics linked to local cellular behavior. Mol Biol Cell 27:1561-9
Trujillo-Provencio, Casilda; Powers, TuShun R; Sultemeier, David R et al. (2016) RNA Extraction from Xenopus Auditory and Vestibular Organs for Molecular Cloning and Expression Profiling with RNA-Seq and Microarrays. Methods Mol Biol 1427:73-92
Ramírez-Gordillo, Daniel; Powers, TuShun R; van Velkinburgh, Jennifer C et al. (2015) RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM(®) genes for hereditary disorders of hearing and balance. BMC Res Notes 8:691
Qian, Wen-Jian; Park, Jung-Eun; Grant, Robert et al. (2015) Neighbor-directed histidine N (?)-alkylation: A route to imidazolium-containing phosphopeptide macrocycles. Biopolymers 104:663-73
Hsu, Albert T; Barrett, Christopher D; DeBusk, George M et al. (2015) Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome. Shock 44:128-36
Dutta, Sanjib; Ryan, Jeremy; Chen, T Scott et al. (2015) Potent and specific peptide inhibitors of human pro-survival protein Bcl-xL. J Mol Biol 427:1241-1253
Landry, Benjamin D; Clarke, David C; Lee, Michael J (2015) Studying Cellular Signal Transduction with OMIC Technologies. J Mol Biol 427:3416-40
Ebrahimkhani, Mohammad R; Neiman, Jaclyn A Shepard; Raredon, Micha Sam B et al. (2014) Bioreactor technologies to support liver function in vitro. Adv Drug Deliv Rev 69-70:132-57

Showing the most recent 10 out of 225 publications