Abstract

Mathematics and Computing. The mathematics/computation core consists of computational facilities, teaching facilities, and core faculty available for consultation. Computational facilities include: a 40 node Linux cluster dedicated specifically to mathematical biology (20 Opteron CPU acquired through the support of the P20 planning grant, and 20 Xeon CPU acquired through the HHMI MCSB program), and an additional 48 node mathematics Linux cluster. These are housed and maintained by the staff of the UCI Network and Academic Computing Services department, and are available for use 24/7. Additional computing power is also available though a large cluster provided for bioinformatics by the Institute for Genomics and Bioinformatics (in which many Center members also participate). The budget includes requests for additional computers in the first few years to augment and update the mathematical biology cluster. Dedicated teaching facilities currently include 12 Linux machines in a teaching lab in the department of Mathematics. These machines are connected and can be used as a cluster. Among the faculty available for consultation, five are directly involved in research projects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM076516-03
Application #
7908919
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2009-08-01
Budget End
2010-07-31
Support Year
3
Fiscal Year
2009
Total Cost
$468,095
Indirect Cost

  Institution

Name
University of California Irvine
Department
Type
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697

  Publications

Mäntylä, Elina; Chacko, Jenu V; Aho, Vesa et al. (2018) Viral highway to nucleus exposed by image correlation analyses. Sci Rep 8:1152
Yan, Huaming; Romero-López, Mónica; Benitez, Lesly I et al. (2018) Multiscale modeling of glioblastoma. Transl Cancer Res 7:S96-S98
Lei, Jinzhi; Nie, Qing; Chen, Dong-Bao (2018) A single-cell epigenetic model for paternal psychological stress-induced transgenerational reprogramming in offspring. Biol Reprod 98:846-855
Huang, Jian; Chen, Long; Rui, Hongxing (2018) Multigrid Methods for A Mixed Finite Element Method of The Darcy-Forchheimer Model. J Sci Comput 74:396-411
Mahlbacher, Grace; Curtis, Louis T; Lowengrub, John et al. (2018) Mathematical modeling of tumor-associated macrophage interactions with the cancer microenvironment. J Immunother Cancer 6:10
McLelland, Bryce T; Lin, Bin; Mathur, Anuradha et al. (2018) Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats. Invest Ophthalmol Vis Sci 59:2586-2603
Davey, Rhonda J; Digman, Michelle A; Gratton, Enrico et al. (2018) Quantitative image mean squared displacement (iMSD) analysis of the dynamics of profilin 1 at the membrane of live cells. Methods 140-141:119-125
Rackauckas, Christopher; Schilling, Thomas; Nie, Qing (2018) Mean-Independent Noise Control of Cell Fates via Intermediate States. iScience 3:11-20
Malacrida, Leonel; Gratton, Enrico (2018) LAURDAN fluorescence and phasor plots reveal the effects of a H2O2 bolus in NIH-3T3 fibroblast membranes dynamics and hydration. Free Radic Biol Med 128:144-156
Malacrida, Leonel; Rao, Estella; Gratton, Enrico (2018) Comparison between iMSD and 2D-pCF analysis for molecular motion studies on in vivo cells: The case of the epidermal growth factor receptor. Methods 140-141:74-84

Showing the most recent 10 out of 404 publications