Abstract

THEME A - CONTROL OF PATTERN (Arthur Lander, Theme Leader) I Understanding pattern?the regular arrangement of cells and cellular behaviors in space?is one of the oldest problems in biology. Over the past half-century, two views of pattern formation have flourished [63,64], both appealing to the actions of molecules, termed morphogens, that spread within tissues. In

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
2P50GM076516-06
Application #
8516153
Study Section
Special Emphasis Panel (ZGM1-CBCB-3 (SB))
Project Start
2007-08-01
Project End
Budget Start
2012-09-25
Budget End
2013-07-31
Support Year
6
Fiscal Year
2012
Total Cost
$333,751
Indirect Cost
$101,430

  Institution

Name
University of California Irvine
Department
Type
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697

  Publications

Mahlbacher, Grace; Curtis, Louis T; Lowengrub, John et al. (2018) Mathematical modeling of tumor-associated macrophage interactions with the cancer microenvironment. J Immunother Cancer 6:10
McLelland, Bryce T; Lin, Bin; Mathur, Anuradha et al. (2018) Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats. Invest Ophthalmol Vis Sci 59:2586-2603
Davey, Rhonda J; Digman, Michelle A; Gratton, Enrico et al. (2018) Quantitative image mean squared displacement (iMSD) analysis of the dynamics of profilin 1 at the membrane of live cells. Methods 140-141:119-125
Rackauckas, Christopher; Schilling, Thomas; Nie, Qing (2018) Mean-Independent Noise Control of Cell Fates via Intermediate States. iScience 3:11-20
Malacrida, Leonel; Gratton, Enrico (2018) LAURDAN fluorescence and phasor plots reveal the effects of a H2O2 bolus in NIH-3T3 fibroblast membranes dynamics and hydration. Free Radic Biol Med 128:144-156
Malacrida, Leonel; Rao, Estella; Gratton, Enrico (2018) Comparison between iMSD and 2D-pCF analysis for molecular motion studies on in vivo cells: The case of the epidermal growth factor receptor. Methods 140-141:74-84
Hedde, Per Niklas; Gratton, Enrico (2018) Selective plane illumination microscopy with a light sheet of uniform thickness formed by an electrically tunable lens. Microsc Res Tech 81:924-928
Kobylkevich, Brian M; Sarkar, Anyesha; Carlberg, Brady R et al. (2018) Reversing the direction of galvanotaxis with controlled increases in boundary layer viscosity. Phys Biol 15:036005
Sameni, Sara; Malacrida, Leonel; Tan, Zhiqun et al. (2018) Alteration in Fluidity of Cell Plasma Membrane in Huntington Disease Revealed by Spectral Phasor Analysis. Sci Rep 8:734
Konstorum, Anna; Lowengrub, John S (2018) Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model. J Theor Biol 439:86-99

Showing the most recent 10 out of 404 publications