Abstract

LIVE IMAGING CORE AND HUB OF INNOVATION Mission The ability to visualize dynamic interactions between bacterial populations and their hosts in live developing animals is an important tool for our proposed Center. The main mission of our Live Imaging Core Facility is to implement advanced microscopy techniques and to develop robust protocols for viewing host-microbe interactions in living animals. Key components are a custom-built light sheet fluorescence microscope and a staff microscopist dedicated to novel instrumentation and to developing new approaches to data analysis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
1P50GM098911-01A1
Application #
8509937
Study Section
Special Emphasis Panel (ZGM1-CBCB-3 (SB))
Project Start
Project End
Budget Start
2012-09-17
Budget End
2013-08-31
Support Year
1
Fiscal Year
2012
Total Cost
$199,804
Indirect Cost
$62,008

  Institution

Name
University of Oregon
Department
Type
DUNS #
948117312
City
Eugene
State
OR
Country
United States
Zip Code
97403

  Publications

Massaquoi, Michelle S; Guillemin, Karen (2018) Evolving in a Microbial Soup: You Are What They Eat. Dev Cell 47:682-683
Logan, Savannah L; Dudley, Christopher; Baker, Ryan P et al. (2018) Automated high-throughput light-sheet fluorescence microscopy of larval zebrafish. PLoS One 13:e0198705
Fahimipour, Ashkaan K; Hartmann, Erica M; Siemens, Andrew et al. (2018) Daylight exposure modulates bacterial communities associated with household dust. Microbiome 6:175
Parthasarathy, Raghuveer (2018) Monitoring microbial communities using light sheet fluorescence microscopy. Curr Opin Microbiol 43:31-37
Hay, Edouard A; Parthasarathy, Raghuveer (2018) Performance of convolutional neural networks for identification of bacteria in 3D microscopy datasets. PLoS Comput Biol 14:e1006628
Stagaman, Keaton; Cepon-Robins, Tara J; Liebert, Melissa A et al. (2018) Market Integration Predicts Human Gut Microbiome Attributes across a Gradient of Economic Development. mSystems 3:
Troll, Joshua V; Hamilton, M Kristina; Abel, Melissa L et al. (2018) Microbiota promote secretory cell determination in the intestinal epithelium by modulating host Notch signaling. Development 145:
Robinson, Catherine D; Klein, Helena S; Murphy, Kyleah D et al. (2018) Experimental bacterial adaptation to the zebrafish gut reveals a primary role for immigration. PLoS Biol 16:e2006893
Miller, Elizabeth Theresa; Svanbäck, Richard; Bohannan, Brendan J M (2018) Microbiomes as Metacommunities: Understanding Host-Associated Microbes through Metacommunity Ecology. Trends Ecol Evol 33:926-935
Burns, A R; Watral, V; Sichel, S et al. (2018) Transmission of a common intestinal neoplasm in zebrafish by cohabitation. J Fish Dis 41:569-579

Showing the most recent 10 out of 46 publications