Abstract

A. PRIMARY FUNCTIONS OF NU SCOR ADMINISTRATIVE COREThe NU SCOR brings together leading investigators in the field from a variety of disciplines and specialties toaddress a major women's health problem, PCOS. The SCOR includes investigators from the Departments ofMedicine, Surgery, Cell and Molecular Biology and the Center for Genetic Medicine at the Feinberg College ofMedicine and from the Department of Neurobiology and Physiology at the Weinberg College of Arts andSciences at Northwestern University. It includes faculty based at Northwestern Memorial Hospital andEvanston Hospital. The Administrative Core will continue to be headed by the Director, Dr. Andrea Dunaif,assisted by the Associate Director, Dr. Jon Levine. The Administrative Core provides leadership, coordinationof activities, and exchange of information, ideas and common resources for Northwestern University's fourSCOR projects. The Administrative Core coordinates educational, training and outreach activities related tothe SCOR as well as joint initiatives with the Northwestern University Center for Reproductive Sciences andthe NICHD Specialized Cooperative Centers Program Reproductive Research (SCCPRR) Center atNorthwestern University. Through these activities, the Administrative Core advances research on sex andgender differences.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center (P50)
Project #
5P50HD044405-07
Application #
7706823
Study Section
Special Emphasis Panel (ZRG1-HOP-U (40))
Project Start
2008-09-01
Project End
2012-08-31
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
7
Fiscal Year
2008
Total Cost
$187,954
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Type
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611

  Publications

Kraynak, Marissa; Colman, Ricki J; Flowers, Matthew T et al. (2018) Ovarian estradiol supports sexual behavior but not energy homeostasis in female marmoset monkeys. Int J Obes (Lond) :
Abbott, David H; Vepraskas, Sarah H; Horton, Teresa H et al. (2018) Accelerated Episodic Luteinizing Hormone Release Accompanies Blunted Progesterone Regulation in PCOS-like Female Rhesus Monkeys (Macaca Mulatta) Exposed to Testosterone during Early-to-Mid Gestation. Neuroendocrinology 107:133-146
Abbott, D H; Rayome, B H; Dumesic, D A et al. (2017) Clustering of PCOS-like traits in naturally hyperandrogenic female rhesus monkeys. Hum Reprod 32:923-936
Sam, Susan; Vellanki, Priyathama; Yalamanchi, Sudha K et al. (2017) Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome. Metabolism 71:125-131
True, Cadence; Abbott, David H; Roberts Jr, Charles T et al. (2017) Sex Differences in Androgen Regulation of Metabolism in Nonhuman Primates. Adv Exp Med Biol 1043:559-574
Kraynak, Marissa; Flowers, Matthew T; Shapiro, Robert A et al. (2017) Extraovarian gonadotropin negative feedback revealed by aromatase inhibition in female marmoset monkeys. Am J Physiol Endocrinol Metab 313:E507-E514
Gibson-Helm, Melanie; Teede, Helena; Dunaif, Andrea et al. (2017) Delayed Diagnosis and a Lack of Information Associated With Dissatisfaction in Women With Polycystic Ovary Syndrome. J Clin Endocrinol Metab 102:604-612
Gorsic, Lidija K; Kosova, Gulum; Werstein, Brian et al. (2017) Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome. J Clin Endocrinol Metab 102:2862-2872
Dunaif, Andrea (2016) Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity. J Clin Endocrinol Metab 101:759-68
Abbott, David H; Levine, Jon E; Dumesic, Daniel A (2016) Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits. Curr Pharm Des 22:5625-5633

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