Abstract

The Cytogenetics Core will perform polytene chromosome in situ hybridizations to polytene chromosomes to serve the needs of the Center's various projects. The primary role of the Cytogenetics Core will be to support the efforts of the map completion project described in Section 2 of the proposal. The Cytogenetics Core will label probes, prepare chromosome squashes, carry out hybridizations, and analyze and record the results of these hybridizations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center (P50)
Project #
2P50HG000750-04
Application #
5213036
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Hoskins, Roger A; Carlson, Joseph W; Wan, Kenneth H et al. (2015) The Release 6 reference sequence of the Drosophila melanogaster genome. Genome Res 25:445-58
Hoskins, Roger A; Carlson, Joseph W; Kennedy, Cameron et al. (2007) Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Science 316:1625-8
Tomancak, Pavel; Berman, Benjamin P; Beaton, Amy et al. (2007) Global analysis of patterns of gene expression during Drosophila embryogenesis. Genome Biol 8:R145
Osoegawa, Kazutoyo; Vessere, Gery M; Li Shu, Chung et al. (2007) BAC clones generated from sheared DNA. Genomics 89:291-9
Yandell, Mark; Mungall, Chris J; Smith, Chris et al. (2006) Large-scale trends in the evolution of gene structures within 11 animal genomes. PLoS Comput Biol 2:e15
George, Janet A; DeBaryshe, P Gregory; Traverse, Karen L et al. (2006) Genomic organization of the Drosophila telomere retrotransposable elements. Genome Res 16:1231-40
Bergman, Casey M; Carlson, Joseph W; Celniker, Susan E (2005) Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruitfly, Drosophila melanogaster. Bioinformatics 21:1747-9
Pollard, Daniel A; Bergman, Casey M; Stoye, Jens et al. (2004) Benchmarking tools for the alignment of functional noncoding DNA. BMC Bioinformatics 5:6
Berman, Benjamin P; Pfeiffer, Barret D; Laverty, Todd R et al. (2004) Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura. Genome Biol 5:R61
Harbison, Susan T; Yamamoto, Akihiko H; Fanara, Juan J et al. (2004) Quantitative trait loci affecting starvation resistance in Drosophila melanogaster. Genetics 166:1807-23

Showing the most recent 10 out of 49 publications