Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL037121-10
Application #
5213628
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Yarovinsky, Timur O; Monick, Martha M; Hunninghake, Gary W (2003) Integrin receptors are crucial for the restimulation of activated T lymphocytes. Am J Respir Cell Mol Biol 28:607-15
Yarovinsky, T O; Hunninghake, G W (2001) Lung fibroblasts inhibit activation-induced death of T cells through PGE(2)-dependent mechanisms. Am J Physiol Lung Cell Mol Physiol 281:L1248-56
Chen, W; Hunninghake, G W (2000) Effects of ragweed and Th-2 cytokines on the secretion of IL-8 in human airway epithelial cells. Exp Lung Res 26:229-39
Geist, L J; Powers, L S; Monick, M M et al. (2000) Asbestos stimulation triggers differential cytokine release from human monocytes and alveolar macrophages. Exp Lung Res 26:41-56
Monick, M M; Carter, A B; Gudmundsson, G et al. (1999) A phosphatidylcholine-specific phospholipase C regulates activation of p42/44 mitogen-activated protein kinases in lipopolysaccharide-stimulated human alveolar macrophages. J Immunol 162:3005-12
Gudmundsson, G; Hunninghake, G W (1999) Respiratory epithelial cells release interleukin-8 in response to a thermophilic bacteria that causes hypersensitivity pneumonitis. Exp Lung Res 25:217-28
Carter, A B; Monick, M M; Hunninghake, G W (1999) Both Erk and p38 kinases are necessary for cytokine gene transcription. Am J Respir Cell Mol Biol 20:751-8
Monick, M M; Carter, A B; Hunninghake, G W (1999) Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity. J Biol Chem 274:18075-80
Gudmundsson, G; Monick, M M; Hunninghake, G W (1999) Viral infection modulates expression of hypersensitivity pneumonitis. J Immunol 162:7397-401
Goebel, E A; Davidson, B L; Graham, S M et al. (1998) Tumor reduction in vivo after adenoviral mediated gene transfer of the herpes simplex virus thymidine kinase gene and ganciclovir treatment in human head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg 119:331-6

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