Abstract

The Biostatistics and Computing Core Unit's primary role is to provide biostatistical collaboration and data management support to the investigators of each SCOR project. This activity will include the experimental design, data management, and data analysis of all projects. One PhD-level statistician (Dr. Wei) and one MS statistician (Ms. Langhough) will devote continuous effort to this program, as well as computing and statistical support staff. The proposed SCOR Biostatistics and Computing Core Unit will be an integral part of the UW Medical School's Biostatistics Center and thus, benefits directly from experience, skills, and resources of that program. The Core Unit's goal is to assure that the results of this SCOR program are of the highest statistical and scientific quality.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL046478-05
Application #
5213878
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Grummer, M A; Zachman, R D (1998) Retinoic acid and dexamethasone affect RAR-beta and surfactant protein C mRNA in the MLE lung cell line. Am J Physiol 274:L1-7
Tsao, F H; Meyer, K C; Chen, X et al. (1998) Degradation of annexin I in bronchoalveolar lavage fluid from patients with cystic fibrosis. Am J Respir Cell Mol Biol 18:120-8
Zimmerman, J J; Gabbert, D; Shivpuri, C et al. (1998) Meter-dosed, inhaled beclomethasone attenuates bronchoalveolar oxyradical inflammation in premature infants at risk for bronchopulmonary dysplasia. Am J Perinatol 15:567-76
Zachman, R D; Grummer, M A (1998) Effect of maternal/fetal vitamin A deficiency on fetal rat lung surfactant protein expression and the response to prenatal dexamethasone. Pediatr Res 43:178-83
Ts'ao, C; Ward, W F; Molteni, A et al. (1997) Annexin I concentration and prostacyclin production in rat lung and alveolar macrophages following irradiation. Prostaglandins Leukot Essent Fatty Acids 56:99-104
Zimmerman, J J; Ciesielski, W; Lewandoski, J (1997) Neutrophil-mediated phospholipid peroxidation assessed by gas chromatography-mass spectroscopy. Am J Physiol 273:C653-61
Contreras, M; Hariharan, N; Lewandoski, J R et al. (1996) Bronchoalveolar oxyradical inflammatory elements herald bronchopulmonary dysplasia. Crit Care Med 24:29-37
Tsao, F H; Cheng, W; Chen, X et al. (1996) Isolation and sequencing of the cDNA encoding phosphatidylinositol transfer protein from rabbit lung. Gene 172:299-302
Zachman, R D; Samuels, D P; Brand, J M et al. (1996) Use of the intramuscular relative-dose-response test to predict bronchopulmonary dysplasia in premature infants. Am J Clin Nutr 63:123-9
Zimmerman, J J (1995) Bronchoalveolar inflammatory pathophysiology of bronchopulmonary dysplasia. Clin Perinatol 22:429-56

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