The Morphology Core Laboratory is a centralized research resource providing SCOR investigators with routine technical service and access to state-of-the-art instrumentation for conducting light and electron microscopic investigations. The facility, now in its fifteenth year of operation, is staffed by a faculty Director and three technicians. The skills and experience of the staff are extensive and complementary. The services of the facility include complete technical support in the preparation and examination of samples by light and electron microscopy, data acquisition, consultation in experimental design, and instruction and assistance in the use of instrumentation. The facility was designed as a dedicated microscopy facility and occupies approximately 2800 sq. Ft. in a new building (occupied in March, 1995). In addition to a wide array of instruments and service resources contained in the laboratory, a number of shared ancillary and support rooms and resources also are available. Funding for the laboratory is based on shared costs with other agencies and organizations proportionate to their use of the facility. This organizational framework provides investigators with access to centralized, sophisticated, and well-maintained resources for conducting a wide variety morphologic investigations in a highly cost effective environment.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL056395-05
Application #
6410548
Study Section
Project Start
2000-12-01
Project End
2002-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
5
Fiscal Year
2001
Total Cost
$196,240
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Mellow, Thomas E; Murphy, Paula C; Carson, Johnny L et al. (2004) The effect of respiratory synctial virus on chemokine release by differentiated airway epithelium. Exp Lung Res 30:43-57
Thai, C H; Gambling, T M; Carson, J L (2002) Freeze fracture study of airway epithelium from patients with primary ciliary dyskinesia. Thorax 57:363-5
Veness-Meehan, Kathleen A; Pierce, Richard A; Moats-Staats, Billie M et al. (2002) Retinoic acid attenuates O2-induced inhibition of lung septation. Am J Physiol Lung Cell Mol Physiol 283:L971-80
Carson, Johnny L; Reed, William; Lucier, Thomas et al. (2002) Axonemal dynein expression in human fetal tracheal epithelium. Am J Physiol Lung Cell Mol Physiol 282:L421-30
Kazachkov, Mikhail Y; Hu, P C; Carson, Johnny L et al. (2002) Release of cytokines by human nasal epithelial cells and peripheral blood mononuclear cells infected with Mycoplasma pneumoniae. Exp Biol Med (Maywood) 227:330-5
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Volberg, T; Romer, L; Zamir, E et al. (2001) pp60(c-src) and related tyrosine kinases: a role in the assembly and reorganization of matrix adhesions. J Cell Sci 114:2279-89
Veness-Meehan, K A; Bottone Jr, F G; Stiles, A D (2000) Effects of retinoic acid on airspace development and lung collagen in hyperoxia-exposed newborn rats. Pediatr Res 48:434-44
Reed, W; Carson, J L; Moats-Staats, B M et al. (2000) Characterization of an axonemal dynein heavy chain expressed early in airway epithelial ciliogenesis. Am J Respir Cell Mol Biol 23:734-41

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