Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL056985-09
Application #
7298281
Study Section
Special Emphasis Panel (ZHL1-CSR-S (F1))
Project Start
2005-04-01
Project End
2007-03-31
Budget Start
2005-04-01
Budget End
2006-03-31
Support Year
9
Fiscal Year
2005
Total Cost
$280,978
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Foks, Amanda C; Engelbertsen, Daniel; Kuperwaser, Felicia et al. (2016) Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol 36:456-65
Wang, Jing; Sukhova, Galina K; Liu, Jian et al. (2015) Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice. J Vasc Surg 62:1615-24
Wang, Jing; Sjöberg, Sara; Tang, Ting-Ting et al. (2014) Cathepsin G activity lowers plasma LDL and reduces atherosclerosis. Biochim Biophys Acta 1842:2174-83
Chen, Han; Wang, Jing; Xiang, Mei-Xiang et al. (2013) Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction. Cardiovasc Res 100:84-94
Lichtman, Andrew H (2013) The heart of the matter: protection of the myocardium from T cells. J Autoimmun 45:90-6
Sun, Jiusong; Sukhova, Galina K; Zhang, Jie et al. (2012) Cathepsin K deficiency reduces elastase perfusion-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol 32:15-23
Griffin, Gabriel K; Newton, Gail; Tarrio, Margarite L et al. (2012) IL-17 and TNF-? sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation. J Immunol 188:6287-99
Tarrio, Margarite L; Grabie, Nir; Bu, De-xiu et al. (2012) PD-1 protects against inflammation and myocyte damage in T cell-mediated myocarditis. J Immunol 188:4876-84
Zhang, Jie; Sun, Jiusong; Lindholt, Jes S et al. (2011) Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation. Circ Res 108:1316-27
Bu, De-xiu; Griffin, Gabriel; Lichtman, Andrew H (2011) Mechanisms for the anti-inflammatory effects of statins. Curr Opin Lipidol 22:165-70

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