Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
1P50HL065967-01
Application #
6473675
Study Section
Special Emphasis Panel (ZHL1)
Project Start
2001-06-06
Project End
2006-01-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Turner, Nancy; Nolasco, Leticia; Moake, Joel (2012) Generation and breakdown of soluble ultralarge von Willebrand factor multimers. Semin Thromb Hemost 38:38-46
Chen, Junmei; Reheman, Adili; Gushiken, Francisca C et al. (2011) N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice. J Clin Invest 121:593-603
Chen, Junmei; Fu, Xiaoyun; Wang, Yi et al. (2010) Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13. Blood 115:706-12
Munday, A D; Gaus, K; López, J A (2010) The platelet glycoprotein Ib-IX-V complex anchors lipid rafts to the membrane skeleton: implications for activation-dependent cytoskeletal translocation of signaling molecules. J Thromb Haemost 8:163-72
Nambi, Vijay; Kimball, Kay T; Bray, Paul F et al. (2009) Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD). Platelets 20:199-205
Shah, Mona D; Bergeron, Angela L; Dong, Jing-Fei et al. (2008) Flow cytometric measurement of microparticles: pitfalls and protocol modifications. Platelets 19:365-72
Yago, Tadayuki; Lou, Jizhong; Wu, Tao et al. (2008) Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF. J Clin Invest 118:3195-207
Moake, Joel L (2007) Journey in reverse: TTP from bedside to blood bank to bench. J Clin Apher 22:37-49
Auton, Matthew; Cruz, Miguel A; Moake, Joel (2007) Conformational stability and domain unfolding of the Von Willebrand factor A domains. J Mol Biol 366:986-1000
Nguyen, Trung C; Liu, Anne; Liu, Li et al. (2007) Acquired ADAMTS-13 deficiency in pediatric patients with severe sepsis. Haematologica 92:121-4

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