Abstract

This Core will provide integral support for the design, data management, statistical analysis, and? interpretation for each of the six projects. In addition, the Core will interact with the data producing Cores C? and D, and the Projects to ensure the quality, reliability, safety, and availability of the relevant data and? results. The Core will provide computational and informatics expertise and facilities to the Projects and other? Cores.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL081011-02
Application #
7493851
Study Section
Special Emphasis Panel (ZHL1)
Project Start
2007-03-01
Project End
2011-02-28
Budget Start
2007-03-01
Budget End
2008-02-29
Support Year
2
Fiscal Year
2007
Total Cost
$185,066
Indirect Cost

  Institution

Name
Cleveland Clinic Lerner
Department
Type
DUNS #
135781701
City
Cleveland
State
OH
Country
United States
Zip Code
44195

  Publications

Wu, M; Barnard, J; Kundu, S et al. (2015) A novel pathway of cellular activation mediated by antiphospholipid antibody-induced extracellular vesicles. J Thromb Haemost 13:1928-40
Hajj-Ali, Rula A; Major, Jennifer; Langford, Carol et al. (2015) The interface of inflammation and subclinical atherosclerosis in granulomatosis with polyangiitis (Wegener's): a preliminary study. Transl Res 166:366-74
Chaturvedi, Shruti; Cockrell, Erin; Espinola, Ricardo et al. (2015) Circulating microparticles in patients with antiphospholipid antibodies: characterization and associations. Thromb Res 135:102-8
Timur, A Anil; Murugesan, Gurunathan; Zhang, Li et al. (2014) Multi-parameter assessment of platelet inhibition and its stability during aspirin and clopidogrel therapy. Thromb Res 134:96-104
Chaturvedi, Shruti; McCrae, Keith R (2014) Recent advances in the antiphospholipid antibody syndrome. Curr Opin Hematol 21:371-9
Zhao, Y; Xiong, Z; Lechner, E J et al. (2014) Thrombospondin-1 triggers macrophage IL-10 production and promotes resolution of experimental lung injury. Mucosal Immunol 7:440-8
Gupta, Nilaksh; Li, Wei; Willard, Belinda et al. (2014) Proteasome proteolysis supports stimulated platelet function and thrombosis. Arterioscler Thromb Vasc Biol 34:160-8
Li, Wei; Gigante, Alba; Perez-Perez, Maria-Jesus et al. (2014) Thymidine phosphorylase participates in platelet signaling and promotes thrombosis. Circ Res 115:997-1006
Srikanthan, S; Li, W; Silverstein, R L et al. (2014) Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions. J Thromb Haemost 12:1906-17
Betapudi, Venkaiah; Lominadze, George; Hsi, Linda et al. (2013) Anti-?2GPI antibodies stimulate endothelial cell microparticle release via a nonmuscle myosin II motor protein-dependent pathway. Blood 122:3808-17

Showing the most recent 10 out of 58 publications