The objective of the Clinical Research Skills Development Core is to develop skilled, productive, andindependent translational and clinical investigators in vascular disease.
Our specific aim i s to train younginvestigators in designing, performing, analyzing and interpreting translational and clinical research toprevent, detect, characterize, and treat/manage vascular disease. Training for each participant will include a)an advanced course on Vascular Biology taught by prominent researchers; b) biweekly SCCOR-TAADseminars led by eminent faculty; c) a Clinical Research Curriculum described on the 'pink sheets' for thecompetitive K30 renewal as 'an extremely sophisticated and successful program.' Basic courses &workshops are given Wednesdays 5-6:30 PM & tailored to help each participant develop & refinetranslational or clinical study protocols, grant proposals, and manuscripts. Advanced courses may be takenat UT Houston Graduate School & Schools of Medicine, Health Informatics, & Public Health; Baylor Collegeof Medicine & Graduate School; & Rice University, all within or adjacent to our Medical Center. Participantswith adequate protected time may pursue an MS in Clinical Research or other MS or PhD degree if importantto their career development; d) a focused program of research with intensive mentorship provided jointlyfrom a primary mentor & a Core mentor providing methodologic expertise in translational or clinical research.Young investigators will be fully involved in a SCCOR-TAAD project, initiate their own research, & within 2years prepare a major research proposal (e.g. a R03, K08, or K23). Intensive mentorship will continuethrough completion of both this research and the SCCOR-TAAD.The Core Director is Jon Tyson, MD, MPH, Bain Professor of Pediatrics & Internal Medicine, Director ofthe Center for Clinical Research and Evidence-Based Medicine, and the 2004 Recipient of the DistinguishedEducator Award from the National Association of Clinical Training Program Directors. The Core Co-Directoris Dianna Milewicz, MD, PhD, Professor of Internal Medicine, Director of Medical Genetics and of theMD/PhD program, & recipient of a Doris Duke Distinguished Clinical Scientist Award. They and other seniorCore mentors and investigators in the SCCOR-TAAD provide the complementary background and talents totrain skilled, productive, and independent translational and clinical investigators in vascular disease. In thisway, our Clinical Research Skills Development Core will help to train the next generation of physicianscientists investigating vascular disease and to translate the advances in basic research into improvedmethods to prevent, diagnose, and treat a common cause of death and disability.
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