Abstract

The goal of the Data and Biostatistics Core is to support all aspects of CCNMD Projects, from inception of the? study aims through publication of the study results. The highest standards possible to insure the integrity of the? data and the results obtained are maintained. To accomplish this, there are four primary functions of this Core:? Data management, Study Design, Data analysis, and Computing. Collectively, these functions provide support? for all aspects of dealing with data, from study design through data analysis and publication of the results, as? well as computing support to facilitate these data functions. The members of the core include biostatisticians,? data management and computing professionals. The biostatistical team includes expertise in the design,? conduct, and analysis of both human and animal studies as well as imaging data. Dr. Warren Bilker will serve as? the Core Director overseeing all activities and personnel. He also collaborates with faculty with expertise? required for implementation of the proposed research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH064045-08
Application #
7656664
Study Section
Special Emphasis Panel (ZMH1)
Project Start
Project End
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
8
Fiscal Year
2008
Total Cost
$185,023
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

van Erp, Theo G M; Walton, Esther; Hibar, Derrek P et al. (2018) Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biol Psychiatry 84:644-654
Walton, E; Hibar, D P; van Erp, T G M et al. (2017) Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium. Acta Psychiatr Scand 135:439-447
Barz, Claudia S; Bessaih, Thomas; Abel, Ted et al. (2016) Sensory encoding in Neuregulin 1 mutants. Brain Struct Funct 221:1067-81
Satterthwaite, Theodore D; Wolf, Daniel H; Calkins, Monica E et al. (2016) Structural Brain Abnormalities in Youth With Psychosis Spectrum Symptoms. JAMA Psychiatry 73:515-24
Welle, Cristin G; Contreras, Diego (2016) Sensory-driven and spontaneous gamma oscillations engage distinct cortical circuitry. J Neurophysiol 115:1821-35
Satterthwaite, Theodore D; Connolly, John J; Ruparel, Kosha et al. (2016) The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth. Neuroimage 124:1115-9
Barz, Claudia S; Bessaih, Thomas; Abel, Ted et al. (2016) Altered resonance properties of somatosensory responses in mice deficient for the schizophrenia risk gene Neuregulin 1. Brain Struct Funct 221:4383-4398
Collier, Azurii K; Wolf, Daniel H; Valdez, Jeffrey N et al. (2014) Comparison of auditory and visual oddball fMRI in schizophrenia. Schizophr Res 158:183-8
Robinson, John L; Molina-Porcel, Laura; Corrada, Maria M et al. (2014) Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old. Brain 137:2578-87
Larimore, Jennifer; Zlatic, Stephanie A; Gokhale, Avanti et al. (2014) Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes. J Biol Chem 289:14291-300

Showing the most recent 10 out of 118 publications