Abstract

Core B is the Biostafistics and Data Management Core which is responsible for developing and maintaining a relational database of demographic, clinical, genetic, biomarker, and other data gathered by SCOR projects described in the application to examine the impact of early life adversity on the development of stress dysregulation. This core provides database, compufing, and biostatistical direction and analysis support to the research pursued in Projects l-lll. Lastly, Core B will employ and extend existing methodologies for the analysis of the SCOR project data.

Public Health Relevance

Early life adversity is one of the greatest predictors of affective disorder onset in women. Core B will provide database, compufing, and biostatistical direcfion and analysis support to the research pursued in Projects I- III.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
3P50MH099910-05S1
Application #
9484361
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Zehr, Julia L
Project Start
Project End
Budget Start
2017-08-01
Budget End
2018-07-31
Support Year
5
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Cooney, Laura G; Milman, Lauren W; Hantsoo, Liisa et al. (2018) Cognitive-behavioral therapy improves weight loss and quality of life in women with polycystic ovary syndrome: a pilot randomized clinical trial. Fertil Steril 110:161-171.e1
Hantsoo, Liisa; Golden, Carla E M; Kornfield, Sara et al. (2018) Startling Differences: Using the Acoustic Startle Response to Study Sex Differences and Neurosteroids in Affective Disorders. Curr Psychiatry Rep 20:40
Bromberger, Joyce T; Epperson, Cynthia Neill (2018) Depression During and After the Perimenopause: Impact of Hormones, Genetics, and Environmental Determinants of Disease. Obstet Gynecol Clin North Am 45:663-678
Hantsoo, Liisa; Criniti, Stephanie; Khan, Annum et al. (2018) A Mobile Application for Monitoring and Management of Depressed Mood in a Vulnerable Pregnant Population. Psychiatr Serv 69:104-107
Nugent, Bridget M; O'Donnell, Carly M; Epperson, C Neill et al. (2018) Placental H3K27me3 establishes female resilience to prenatal insults. Nat Commun 9:2555
Chan, Jennifer C; Nugent, Bridget M; Bale, Tracy L (2018) Parental Advisory: Maternal and Paternal Stress Can Impact Offspring Neurodevelopment. Biol Psychiatry 83:886-894
Kornfield, Sara L; Kang-Yi, Christina D; Mandell, David S et al. (2018) Predictors and Patterns of Psychiatric Treatment Dropout During Pregnancy Among Low-Income Women. Matern Child Health J 22:226-236
Epperson, C Neill; Sammel, Mary D; Bale, Tracy L et al. (2017) Adverse Childhood Experiences and Risk for First-Episode Major Depression During the Menopause Transition. J Clin Psychiatry 78:e298-e307
Freeman, Anne; Stanko, Patrick; Berkowitz, Lily N et al. (2017) Inclusion of sex and gender in biomedical research: survey of clinical research proposed at the University of Pennsylvania. Biol Sex Differ 8:22
Kornfield, Sara L; Moseley, Marian; Appleby, Dina et al. (2017) Posttraumatic Symptom Reporting and Reported Cigarette Smoking During Pregnancy. J Womens Health (Larchmt) 26:662-669

Showing the most recent 10 out of 63 publications