Abstract

The Data Management, Biostatistics and Epidemiology Core will support all of the brain trauma research center projects with statistical analysis and data management. The Core has and will continue to collaborate in the design of the projects, including sample size calculation, definition of measurements and quality control. For clinical projects the Core will manage the data and perform statistical analysis. For laboratory projects the Core investigators will advise on data management and analysis and, if necessary, assist in carrying out analysis. The Core will collaborate with project investigators to prepare reports of study results. An additional responsibility will be to collaborate with other NINDS head injury centers and contribute data to a common patient database.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
2P50NS030318-06
Application #
6243708
Study Section
Project Start
1997-03-01
Project End
1998-02-28
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
6
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Ikonomovic, Milos D; Mi, Zhiping; Abrahamson, Eric E (2017) Disordered APP metabolism and neurovasculature in trauma and aging: Combined risks for chronic neurodegenerative disorders. Ageing Res Rev 34:51-63
Osier, Nicole D; Bales, James W; Pugh, Bunny et al. (2017) Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury. J Neurotrauma 34:86-96
Jackson, Edwin K; Kotermanski, Shawn E; Menshikova, Elizabeth V et al. (2017) Adenosine production by brain cells. J Neurochem 141:676-693
Willyerd, F Anthony; Empey, Philip E; Philbrick, Ashley et al. (2016) Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans. J Neurotrauma 33:226-31
Janata, Andreas; Magnet, Ingrid A M; Uray, Thomas et al. (2014) Regional TNF? mapping in the brain reveals the striatum as a neuroinflammatory target after ventricular fibrillation cardiac arrest in rats. Resuscitation 85:694-701
Drabek, Tomas; Janata, Andreas; Wilson, Caleb D et al. (2014) Minocycline attenuates brain tissue levels of TNF-? produced by neurons after prolonged hypothermic cardiac arrest in rats. Resuscitation 85:284-91
Alexander, Sheila A; Ren, Dianxu; Gunn, Scott R et al. (2014) Interleukin 6 and apolipoprotein E as predictors of acute brain dysfunction and survival in critical care patients. Am J Crit Care 23:49-57
Conley, Yvette P; Okonkwo, David O; Deslouches, Sandra et al. (2014) Mitochondrial polymorphisms impact outcomes after severe traumatic brain injury. J Neurotrauma 31:34-41
Abrahamson, Eric E; Foley, Lesley M; Dekosky, Steven T et al. (2013) Cerebral blood flow changes after brain injury in human amyloid-beta knock-in mice. J Cereb Blood Flow Metab 33:826-33
Cousar, J'mir L; Conley, Yvette P; Willyerd, F Anthony et al. (2013) Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury. Neurocrit Care 19:192-8

Showing the most recent 10 out of 116 publications