Abstract

The purpose of this Core is to collect and store specimens for SPOTRIAS projects, and for possible future studies. Project I requires blood to be drawn, spun, and frozen at several time points. In the larger SPOTRIAS network, there will arise other proposals for specimen collection. We intend to collect and store sufficient blood for our internal, and any external, projects. Further, this core will provide the support needed to collect other tissue as may be required by other investigators. We will address 2 specific aims: 1) To obtain, process and store blood specimens from acute stroke patients. We will establish routine procedures so that blood is obtained on selected Code Stroke patients at multiple time points. The blood will be spun and the serum frozen and stored at -70C. 2) To participate in the national SPOTRIAS network to review additional requests for specimens. A policy for selecting among requests will be formulated so those projects may be evaluated objectively.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
1P50NS044148-01A1
Application #
6751843
Study Section
Special Emphasis Panel (ZNS1-SRB-K (03))
Project Start
2003-05-19
Project End
2008-04-30
Budget Start
2003-05-19
Budget End
2004-04-30
Support Year
1
Fiscal Year
2003
Total Cost
$153,526
Indirect Cost

  Institution

Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Chen, P M; Nguyen, D T; Ho, J P et al. (2018) Factors Influencing Acute Stroke Thrombolytic Treatments in Hispanics In the San Diego Region. Austin J Cerebrovasc Dis Stroke 5:
Lyden, Patrick; Hemmen, Thomas; Grotta, James et al. (2016) Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2). Stroke 47:2888-2895
Guluma, Kama Z; Liebeskind, David S; Raman, Rema et al. (2015) Feasibility and Safety of Using External Counterpulsation to Augment Cerebral Blood Flow in Acute Ischemic Stroke-The Counterpulsation to Upgrade Forward Flow in Stroke (CUFFS) Trial. J Stroke Cerebrovasc Dis 24:2596-604
Neil, William P; Raman, Rema; Hemmen, Thomas M et al. (2015) Association of Hispanic ethnicity with acute ischemic stroke care processes and outcomes. Ethn Dis 25:19-23
Schlick, Konrad H; Hemmen, Thomas M; Lyden, Patrick D (2015) Seizures and Meperidine: Overstated and Underutilized. Ther Hypothermia Temp Manag 5:223-7
Spokoyny, Ilana; Raman, Rema; Ernstrom, Karin et al. (2015) Defining mild stroke: outcomes analysis of treated and untreated mild stroke patients. J Stroke Cerebrovasc Dis 24:1276-81
Spokoyny, Ilana; Raman, Rema; Ernstrom, Karin et al. (2015) Accuracy of First Recorded ""Last Known Normal"" Times of Stroke Code Patients. J Stroke Cerebrovasc Dis 24:2467-73
Coffman, Clarity R; Raman, Rema; Ernstrom, Karin et al. (2015) The ""DeyeCOM Sign"": Predictive Value in Acute Stroke Code Evaluations. J Stroke Cerebrovasc Dis 24:1299-304
Lyden, Patrick D; Hemmen, Thomas M; Grotta, James et al. (2014) Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol. Int J Stroke 9:117-25
Spokoyny, Ilana; Raman, Rema; Ernstrom, Karin et al. (2014) Imaging negative stroke: diagnoses and outcomes in intravenous tissue plasminogen activator-treated patients. J Stroke Cerebrovasc Dis 23:1046-50

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