The purpose of this Core is to develop the careers of clinically trained research scientists along tracksconsonant with the translational research mission and goals of the UCSD SPOTRIAS Center. The trainingFellowship is designed for neurologists or other stroke specialists who wish to obtain postgraduate training instatistics, clinical trials research methods, experimental design, and regulatory requirements. We believe thatthese elements are needed to develop a new generation of clinicians in translational stroke research andtherapy who have sufficient skills and experience to become independent investigators. Training is available intwo fundamental tracks: (1) clinical investigation of stroke therapies and (2) clinical and laboratory-basedinvestigations of experimental stroke. The proportion of time spent in each area varies according to thetrainees' levels of interest, and which track they choose.The UCSD SPOTRIAS Center offers 1- or 2-year training opportunities for PG-5 year or higher individuals.Training in all aspects of translational stroke research is provided, including staffing the Acute Stroke Team.Fellows gain experience with thrombolysis at all of our participating hospitals. Didactic lectures and seminarsare offered in stroke epidemiology, prevention, biochemistry and molecular biology, therapy, statistics, andclinical trial design. If appropriate to prior training, laboratory research opportunities are available. The trainingis intended to provide all the knowledge and skills needed to establish a successful stroke centerindependently in the Fellow's post-training career.Substantive advancement in stroke care requires a cadre of young, skilled, active physician strokespecialists who will champion translational stroke research, ensuring rapid delivery of proven thrombolyticdrugs and rapid development of new, promising adjunctive therapies. The UCSD Stroke Center VascularNeurology Fellowship, which received ACGME accreditation in 2006, is designed to meet this urgent need.The Stroke Center annually recruits 2 physician-Fellows into a state-of-the-art program tailored to train futureCalifornia and national leaders in stroke research and clinical care. To date 18 of the 19 graduates of theStroke Center Fellows Program have become independent investigators or directors of dedicated regionalstroke centers and have taken the lead in ensuring the widest possible application of proven and emergingstroke therapies.
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