: This mission-critical Core will facilitate rapid presentation, assessment, and treatment of acute stroke patients, assuring rapid recruitment of patients for the clinical research studies in Projects 1-3, and ensuring a minimum of 12 patients will be treated with IV TPA within 2 hrs. of onset in each Award year. The Patient Access Core's mission will be achieved through four specific aims.
Aim 1 is to educate individuals at risk in the catchment areas of UCLA Medical Center, UCLA Stroke Network Hospitals, and throughout the City of Los Angeles regarding stroke warning signs, steps to take if symptoms occur, and the importance of early treatments for brain attack.
This aim will be accomplished through lectures, outreach programs, health fairs, and additional educational programs in UCLA Medical Center and UCLA Stroke Network Hospital catchment areas, and throughout Los Angeles.
Aim 2 is to educate prehospital care personnel in the catchment areas of UCLA Medical Center UCLA Stroke Network Hospitals, and throughout the City of Los Angeles regarding stroke recognition, pre-hospital stroke treatment, field pre-notification of receiving hospitals, and the importance of rapid transport.
This aim will be accomplished by educating paramedics citywide in the use of the Los Angeles Prehospital Stroke Screen (LAPSS) and the Los Angeles Motor Scale (LAMS), and by design, validation, and dissemination of a dispatcher version of the LAPSS.
Aim 3 is to optimize rapid Emergency Department and in-hospital management of acute stroke patients at UCLA Medical Center, UCLA Stroke Network Hospitals, and throughout the City of Los Angeles.
This aim will be achieved by expanding rapid response acute stroke team activities at UCLA Medical Center and UCLA Network Stroke hospitals.
Aim 4 is to ensure early patient screening for participation in the three UCLA SPOTRIAS Center research Projects, and additional acute stroke clinical research endeavors at UCLA Medical Center and UCLA Stroke Network Hospitals.
This aim will be achieved by facilitating rapid patient identification, approach for consent, study recruitment, enrollment and longitudinal follow-up evaluations. Targeted programs will promote the recruitment of substantial cohorts of women, Hispanic-Americans, African-Americans, and other minority populations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS044378-03
Application #
7553857
Study Section
Special Emphasis Panel (ZNS1)
Project Start
Project End
Budget Start
2005-06-01
Budget End
2006-05-31
Support Year
3
Fiscal Year
2005
Total Cost
$174,566
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Bevers, Matthew B; Battey, Thomas W K; Ostwaldt, Ann-Christin et al. (2018) Apparent Diffusion Coefficient Signal Intensity Ratio Predicts the Effect of Revascularization on Ischemic Cerebral Edema. Cerebrovasc Dis 45:93-100
Lou, Xin; Yu, Songlin; Scalzo, Fabien et al. (2017) Multi-delay ASL can identify leptomeningeal collateral perfusion in endovascular therapy of ischemic stroke. Oncotarget 8:2437-2443
Nael, Kambiz; Knitter, James R; Jahan, Reza et al. (2017) Multiparametric Magnetic Resonance Imaging for Prediction of Parenchymal Hemorrhage in Acute Ischemic Stroke After Reperfusion Therapy. Stroke 48:664-670
Sheth, Sunil A; Jahan, Reza; Levy, Elad I et al. (2016) Rapid learning curve for Solitaire FR stent retriever therapy: evidence from roll-in and randomised patients in the SWIFT trial. J Neurointerv Surg 8:347-52
Vespa, Paul; Hanley, Daniel; Betz, Joshua et al. (2016) ICES (Intraoperative Stereotactic Computed Tomography-Guided Endoscopic Surgery) for Brain Hemorrhage: A Multicenter Randomized Controlled Trial. Stroke 47:2749-2755
Chaisinanunkul, Napasri; Adeoye, Opeolu; Lewis, Roger J et al. (2015) Adopting a Patient-Centered Approach to Primary Outcome Analysis of Acute Stroke Trials Using a Utility-Weighted Modified Rankin Scale. Stroke 46:2238-43
Guluma, Kama Z; Liebeskind, David S; Raman, Rema et al. (2015) Feasibility and Safety of Using External Counterpulsation to Augment Cerebral Blood Flow in Acute Ischemic Stroke-The Counterpulsation to Upgrade Forward Flow in Stroke (CUFFS) Trial. J Stroke Cerebrovasc Dis 24:2596-604
Shi, Zhong-Song; Duckwiler, Gary R; Jahan, Reza et al. (2015) New Cerebral Microbleeds After Mechanical Thrombectomy for Large-Vessel Occlusion Strokes. Medicine (Baltimore) 94:e2180
Yu, Songlin; Liebeskind, David S; Dua, Sumit et al. (2015) Postischemic hyperperfusion on arterial spin labeled perfusion MRI is linked to hemorrhagic transformation in stroke. J Cereb Blood Flow Metab 35:630-7
Khatri, Pooja; Hacke, Werner; Fiehler, Jens et al. (2015) State of acute endovascular therapy: report from the 12th thrombolysis, thrombectomy, and acute stroke therapy conference. Stroke 46:1727-34

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