This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.We have collected and processed 1517 samples out of a total population of 1,683 from our Indian rhesus breeding colonies for DNA extraction to ascertain the parentage of animals living at the Yerkes Field Station. This includes our entire SPF colonies (n=736) and our NSPF research breeding colonies (n=947). We are in the process of collecting the remaining 166 samples necessary to complete the entire Yerkes rhesus population. We have collected 289 samples from our three mangabey colonies, 68 from our SPF colony, and the remaining 221 from our NSPF colonies. These last remaining samples are currently being analyzed.Our ultimate goal is to ascertain the parentage, pedigree, and selected genetic markers for all of our macaques and mangabeys maintained at the Field Station. The ability to characterize specific genetic components will enable us to better meet specific investigator needs, and genetic profiling will open the door for more diverse research endeavors, to selectively breed for specific genetic traits, and to undertake specific phenotypic comparisons.To manage this data set, we are establishing a full-scale database system that will be able to assimilate genetic, parentage, pedigree, and demographic variables on all the animals. This database system will be incorporated into our current animal records system, which will enable Yerkes' investigators and veterinarians to track, manage, and view an animal's record with a single query.
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